Effect of Modified Pulsatilla Powder on Enterotoxigenic Escherichia coli O101-Induced Diarrhea in Mice

被引：11

作者：

Yu, Jiankang ^{[1
]}

Zhang, Yuetian ^{[1
]}

Song, Xu ^{[1
]}

Yang, Yi ^{[1
]}

Jia, Renyong ^{[1
]}

Chen, Xu ^{[1
]}

Sun, Kai ^{[1
]}

Li, Li ^{[1
]}

Zhao, Xinghong ^{[1
]}

Cui, Qiankun ^{[1
]}

Fu, Qiuting ^{[1
]}

Zou, Yuanfeng ^{[1
]}

Li, Lixia ^{[1
]}

Yin, Zhongqiong ^{[1
]}

机构：

[1] Sichuan Agr Univ, Coll Vet Med, Nat Med Res Ctr, Chengdu 611130, Peoples R China

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2017年 / 2017卷

基金：

中国国家自然科学基金;

关键词：

ANTIDIARRHEAL ACTIVITY; LEAF EXTRACT; POLYSACCHARIDES; IMMUNITY; ENHANCE; INFLAMMATION; MICROFLORA; SAPONINS; BACTERIA; THYMUS;

D O I：

10.1155/2017/3687486

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

MPP can be effective in the treatment of E. coli O101-induced diarrhea in mice. MPP can improve the weight loss caused by diarrhea, increase spleen and thymus indices, and reduce the diarrhea index. MPP can reduce the number of WBC, regulate the level of cytokines, and regulate the intestinal microbial flora. These data suggest that MPP is a promising candidate for treatment of E. coli-induced diarrhea in humans and animals.

引用

页数：11

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