The Epidemiology of Dementia Associated with Parkinson's Disease

被引:201
|
作者
Aarsland, Dag [1 ,4 ,5 ]
Kurz, Martin Wilhelm [2 ,3 ]
机构
[1] Stavanger Univ Hosp, Dept Psychiat, N-4068 Stavanger, Norway
[2] Stavanger Univ Hosp, Dept Neurol, N-4068 Stavanger, Norway
[3] Stavanger Univ Hosp, Norwegian Ctr Movement Disorders, N-4068 Stavanger, Norway
[4] Univ Oslo, Akershus Univ Hosp, Div Mental Hlth Serv, N-1478 Lorenskog, Norway
[5] Univ Oslo, Inst Clin Med, N-1478 Lorenskog, Norway
关键词
dementia; epidemiology; Parkinson's disease; MILD COGNITIVE IMPAIRMENT; SLEEP BEHAVIOR DISORDER; ALPHA-SYNUCLEIN; INCIDENT DEMENTIA; RISK-FACTORS; APOLIPOPROTEIN-E; VISUAL HALLUCINATIONS; SYDNEY MULTICENTER; PREDICT DEMENTIA; TAU-SYNUCLEIN;
D O I
10.1111/j.1750-3639.2009.00369.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Parkinson's disease (PD) is the second most common neurodegenerative illness after Alzheimer's disease (AD). Cognitive impairment and dementia are common features in PD and characterized by a wide range of cognitive deficits distinct from those seen in AD. Mild cognitive impairment occurs even early in PD and is associated with shorter time to dementia. The purpose of this review is to present recent findings on clinical aspects of dementia in PD and to elucidate underlying clinical and neurobiological risk factors.
引用
收藏
页码:633 / 639
页数:7
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