Quetiapine (Seroquel) in the treatment of psychosis in patients with Parkinson's disease

被引：66

作者：

Parsa, MA ^{[1
]}

Bastani, B ^{[1
]}

机构：

[1] Case Western Reserve Univ, Dept Psychiat, Cleveland, OH 44106 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 1998年 / 10卷 / 02期

关键词：

D O I：

10.1176/jnp.10.2.216

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Psychoses are a common clinical problem in patients with Parkinson's disease. Treatment with typical neuroleptics or withdrawal of antiparkinsonian drugs may improve mental symptoms but will worsen the parkinsonism. Quetiapine (Seroquel), ICI 204,636, is a novel antipsychotic medication with a low potential for producing extrapyramidal side effects. In this open-label clinical study of 2 patients with Parkinson's disease, treatment with Seroquel successfully controlled psychotic symptoms without worsening of motor disability.

引用

页码：216 / 219

页数：4

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