Synthesis and characterization of some novel 7-substitued Benzopyrano [3,4-d]imidazoles derivatives

被引：0
|
作者：
Sadhana, K. [1 ]
Aruna, S. [2 ]
机构：
[1] Adhi Coll Engn & Technol, Kancheepuram, Tamil Nadu, India
[2] Queen Marys Coll, PG & Res Dept Chem, Chennai, Tamil Nadu, India
来源：
MATERIALS TODAY-PROCEEDINGS | 2021年 / 45卷
关键词：
7-Substitued coumarins; Bromination; Urea; Thiourea; COUMARIN; AFFINITY; DESIGN;
D O I：
10.1016/j.matpr.2021.01.427
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Imidazole and coumarin are most widely used heterocyclic scaffolds which are used in synthesis of drug molecules. A series of 7-subsitituted coumarins have been synthesized by route of substitution and condensation reactions of 1 mol of 2,3-dibromodihydrocoumarines and 2 mol of urea and thiourea in ethanol as a solvent. The reactions were carried out thermally as well as by irradiation with microwave. Structure elucidation of these newly designed compounds have been confirmed by basis of IR, H-1 NMR, C-13 NMR, Mass spectral datas. This novel method involved simple experimental procedure, short time and excellent yield. (C) 2020 Elsevier Ltd. All rights reserved.
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页码：6969 / 6973
页数：5
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