The Gut Microbiota as a Mediator of Metabolic Benefits after Bariatric Surgery

被引:65
|
作者
Anhe, Fernando F. [1 ,2 ]
Varin, Thibault V. [2 ]
Schertzer, Jonathan D. [3 ,4 ]
Marette, Andre [1 ,2 ]
机构
[1] Quebec Heart & Lung Inst, Cardiol Axis, Fac Med, Dept Med, Quebec City, PQ, Canada
[2] Laval Univ, Inst Nutr & Funct Foods, Quebec City, PQ, Canada
[3] McMaster Univ, Dept Biochem & Biomed Sci, Hamilton, ON, Canada
[4] McMaster Univ, Farncombe Family Digest Hlth Res Inst, Hamilton, ON, Canada
关键词
gastric bypass; glycemic control and bile acids; Roux-en-Y; sleeve gastrectomy; Y GASTRIC BYPASS; CONJUGATED BILE-ACIDS; WEIGHT-LOSS; INSULIN SENSITIVITY; ESCHERICHIA-COLI; OBESE-PATIENTS; BILIOPANCREATIC DIVERSION; AKKERMANSIA-MUCINIPHILA; INTESTINAL MICROBIOTA; GLYCEMIC CONTROL;
D O I
10.1016/j.jcjd.2017.02.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bariatric surgery is based on major anatomic rearrangements in the gastrointestinal tract that coincide with functional and taxonomic changes in gut microbial communities. These alterations in gut anatomy and in the microbiota are associated with early resolution of obesity-related impairment of glycemic control and are marked weight loss in the long term. Moreover, altered bile acid metabolism has been implicated in the control of energy homeostasis, emerging as a pivotal orchestrator in the gut microbiota-mediated effects of bariatric surgery. In this review, we summarize the growing body of evidence linking changes in the gut microbiota to the metabolic benefits of bariatric surgery and discuss the potential mechanisms involved. (C) 2017 Canadian Diabetes Association.
引用
收藏
页码:439 / 447
页数:9
相关论文
共 50 条
  • [1] Modification of fecal microbiota as a mediator of effective weight loss and metabolic benefits following bariatric surgery
    Oduro-Donkor, Dominic
    Turner, Mark C.
    Farnaud, Sebastien
    Renshaw, Derek
    Kyrou, Ioannis
    Hanson, Petra
    Hattersley, John
    Weickert, Martin O.
    Menon, Vinod
    Randeva, Harpal S.
    Barber, Thomas M.
    [J]. EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM, 2020, 15 (05) : 363 - 373
  • [2] The importance of the gut microbiota after bariatric surgery
    Aron-Wisnewsky, Judith
    Dore, Joel
    Clement, Karine
    [J]. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2012, 9 (10) : 590 - 598
  • [3] The importance of the gut microbiota after bariatric surgery
    Judith Aron-Wisnewsky
    Joel Doré
    Karine Clement
    [J]. Nature Reviews Gastroenterology & Hepatology, 2012, 9 : 590 - 598
  • [4] DIFFERENCES OF GUT MICROBIOTA & EXTRACELLULAR VESICLES AFTER BARIATRIC/METABOLIC SURGERY Basic science and research in bariatric surgery
    Lee, J. H.
    Huh, Y. J.
    [J]. OBESITY SURGERY, 2017, 27 : 212 - 212
  • [5] Gut microbiota in bariatric surgery
    Gasmi, Amin
    Bjorklund, Geir
    Mujawdiya, Pavan Kumar
    Semenova, Yuliya
    Dosa, Alexandru
    Piscopo, Salva
    Pen, Joeri J.
    Benahmed, Asma Gasmi
    Costea, Daniel-Ovidiu
    [J]. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2023, 63 (28) : 9299 - 9314
  • [6] Altered gut microbiome after bariatric surgery and its association with metabolic benefits: A systematic review
    Davies, Naomi K.
    O'Sullivan, Justin M.
    Plank, Lindsay D.
    Murphy, Rinki
    [J]. SURGERY FOR OBESITY AND RELATED DISEASES, 2019, 15 (04) : 656 - 665
  • [7] Gut microbiota turn up the heat after bariatric surgery
    Hankir, Mohammed K.
    [J]. CELL STRESS, 2023, 7 (10) : 90 - 94
  • [8] Diet, Bariatric Surgery and Gut Microbiota
    Ozdemir, Aslihan
    Buyuktuncer, Zehra
    [J]. ISTANBUL MEDICAL JOURNAL, 2018, 19 (03): : 208 - 213
  • [9] GUT MICROBIOTA AND ITS POTENTIAL ROLE IN IMPROVING METABOLIC OUTCOMES OF BARIATRIC SURGERY
    Hatami, Mahsa
    Pazouki, Abdolreza
    [J]. OBESITY SURGERY, 2023, 33 : 142 - 142
  • [10] Gut microbiota characterisation in obese patients before and after bariatric surgery
    Campisciano, G.
    Palmisano, S.
    Cason, C.
    Giuricin, M.
    Silvestri, M.
    Guerra, M.
    Macor, D.
    De Manzini, N.
    Croce, L. S.
    Comar, M.
    [J]. BENEFICIAL MICROBES, 2018, 9 (03) : 367 - 373