Impact of selected cell culture media and different HEK293 production cell lines on the expression of a variety of recombinant adeno associated virus subtypes

被引:0
|
作者
Kraus, B. [1 ]
Kahlig, C. [1 ]
Micutkova, L. [1 ]
Siegwart, G. [1 ]
Bort, J. A. Hernandez [1 ]
机构
[1] Baxalta Shire HGT Inc, Gene Therapy Ctr Austria, Vienna, Austria
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
P234
引用
收藏
页码:A88 / A88
页数:1
相关论文
共 50 条
  • [1] Impact of Selected Cell Culture Media and Different HEK293 Production Cell Lines on the Expression of a Variety of Recombinant Adeno Associated Virus Subtypes
    Kraus, Barbara
    Kahlig, Carolin
    Micutkova, Lucia
    Siegwart, Gerald
    Bort, Juan Hernandez
    MOLECULAR THERAPY, 2019, 27 (04) : 350 - 350
  • [2] Process modeling of recombinant adeno-associated virus production in HEK293 cells
    Joiner, Jordan
    Huang, Zhuangrong
    McHugh, Kyle
    Stebbins, Matthew
    Aron, Kathryn
    Borys, Michael
    Khetan, Anurag
    CURRENT OPINION IN CHEMICAL ENGINEERING, 2022, 36
  • [3] Characterisation of mRNA expression patterns of different HEK293 cell lines used for virus-like particles production
    Pistek, M.
    Kahlig, C. I.
    Kraus, B.
    Bort, J. A. Hernandez
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A114 - A114
  • [4] HEK293 cell culture media study: increasing cell density for different bioprocess applications
    Leticia Liste-Calleja
    Martí Lecina
    Jordi Joan Cairó
    BMC Proceedings, 7 (Suppl 6)
  • [5] Impact of Genome Accessibility and Long-Term Expression of Adeno-Associated Virus 5 Produced in Mammalian (HEK293) and Insect (Sf) Cell Lines
    Ismail, Ashrafali M.
    Handyside, Britta
    Zhang, Lening
    Yates, Bridget
    Xie, Lin
    Sihn, Choong-Ryoul
    Murphy, Ryan
    Bouwman, Taren
    Ngo, Katina
    Woloszynek, Jill
    Colosi, Peter
    Bullens, Sherry
    Bunting, Stuart
    Fong, Sylvia
    MOLECULAR THERAPY, 2022, 30 (04) : 432 - 432
  • [6] Transcriptomic features reveal molecular signatures associated with recombinant adeno-associated virus production in HEK293 cells
    Wang, Yongdan
    Fu, Qiang
    Lee, Yong Suk
    Sha, Sha
    Yoon, Seongkyu
    BIOTECHNOLOGY PROGRESS, 2023, 39 (04)
  • [7] Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells
    Nguyen, Tam N. T.
    Sha, Sha
    Hong, Moo Sun
    Maloney, Andrew J.
    Barone, Paul W.
    Neufeld, Caleb
    Wolfrum, Jacqueline
    Springs, Stacy L.
    Sinskey, Anthony J.
    Braatz, Richard D.
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021, 21 : 642 - 655
  • [8] Long-term Expression Comparison of Adeno-Associated Virus (AAV) Vector Produced in HEK293 vs Sf Cell Lines
    Handyside, Britta
    Zhang, Lening
    Yates, Bridget
    Xie, Lin
    Sihn, Choong-Ryoul
    Murphy, Ryan
    Bouwman, Taren
    Ngo, Katina
    Kaplowitz, Brian
    Fredette, Natalie
    Gorostiza, Olivia
    Baridon, Brian
    Agrawal, Vishal
    Cortesio, Christa
    Akeefe, Hassib
    Woloszynek, Jill
    Su, Cheng
    Zhang, Weiming
    Colosi, Peter
    Bullens, Sherry
    Veres, Gabor
    Bunting, Stuart
    Fong, Sylvia
    MOLECULAR THERAPY, 2021, 29 (04) : 118 - 118
  • [9] Increased recombinant adeno-associated virus production by HEK293 cells using small molecule chemical additives
    Scarrott, Joseph M.
    Johari, Yusuf B.
    Pohle, Thilo H.
    Liu, Ping
    Mayer, Ayda
    James, David C.
    BIOTECHNOLOGY JOURNAL, 2023, 18 (03)
  • [10] Transcriptional Response of HEK293 cells to Clinical-Scale Recombinant Adeno Associated Virus Production by Transient Transfection
    Chung, Cheng-Han
    Murphy, Christopher
    McCarty, Douglas
    Pavlicek, Jeffrey
    Barton, Erik
    MOLECULAR THERAPY, 2021, 29 (04) : 62 - 62