Deep into Laboratory: An Artificial Intelligence Approach to Recommend Laboratory Tests
被引:13
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作者:
Islam, Md. Mohaimenul
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机构:
Taipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Taipei Med Univ, Int Ctr Hlth Informat Technol ICHIT, Taipei 110, Taiwan
Taipei Med Univ, Wan Fang Hosp, Res Ctr Big Data & Meta Anal, Taipei 116, TaiwanTaipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Islam, Md. Mohaimenul
[1
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Poly, Tahmina Nasrin
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机构:
Taipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Taipei Med Univ, Int Ctr Hlth Informat Technol ICHIT, Taipei 110, Taiwan
Taipei Med Univ, Wan Fang Hosp, Res Ctr Big Data & Meta Anal, Taipei 116, TaiwanTaipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Poly, Tahmina Nasrin
[1
,2
,3
]
Yang, Hsuan-Chia
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机构:
Taipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Taipei Med Univ, Int Ctr Hlth Informat Technol ICHIT, Taipei 110, Taiwan
Taipei Med Univ, Wan Fang Hosp, Res Ctr Big Data & Meta Anal, Taipei 116, TaiwanTaipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Yang, Hsuan-Chia
[1
,2
,3
]
Li, Yu-Chuan
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机构:
Taipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Taipei Med Univ, Int Ctr Hlth Informat Technol ICHIT, Taipei 110, Taiwan
Taipei Med Univ, Wan Fang Hosp, Res Ctr Big Data & Meta Anal, Taipei 116, Taiwan
Wan Fang Hosp, Dept Dermatol, Taipei 116, Taiwan
Taipei Med Univ, TMU Res Ctr Canc Translat Med, Taipei 110, TaiwanTaipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
Li, Yu-Chuan
[1
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机构:
[1] Taipei Med Univ, Grad Inst Biomed Informat, Coll Med Sci & Technol, Taipei 110, Taiwan
[2] Taipei Med Univ, Int Ctr Hlth Informat Technol ICHIT, Taipei 110, Taiwan
[3] Taipei Med Univ, Wan Fang Hosp, Res Ctr Big Data & Meta Anal, Taipei 116, Taiwan
[4] Wan Fang Hosp, Dept Dermatol, Taipei 116, Taiwan
[5] Taipei Med Univ, TMU Res Ctr Canc Translat Med, Taipei 110, Taiwan
laboratory test;
deep learning;
artificial intelligence;
recommendation system;
clinical decision support system;
PRIMARY-CARE;
HEALTH;
PHYSICIANS;
DEMAND;
TRENDS;
COST;
D O I:
10.3390/diagnostics11060990
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Laboratory tests are performed to make effective clinical decisions. However, inappropriate laboratory test ordering hampers patient care and increases financial burden for healthcare. An automated laboratory test recommendation system can provide rapid and appropriate test selection, potentially improving the workflow to help physicians spend more time treating patients. The main objective of this study was to develop a deep learning-based automated system to recommend appropriate laboratory tests. A retrospective data collection was performed at the National Health Insurance database between 1 January 2013, and 31 December 2013. We included all prescriptions that had at least one laboratory test. A total of 1,463,837 prescriptions from 530,050 unique patients was included in our study. Of these patients, 296,541 were women (55.95%), the range of age was between 1 and 107 years. The deep learning (DL) model achieved a higher area under the receiver operating characteristics curve (AUROC micro = 0.98, and AUROC macro = 0.94). The findings of this study show that the DL model can accurately and efficiently identify laboratory tests. This model can be integrated into existing workflows to reduce under- and over-utilization problems.
机构:
Chinese Acad Med Sci, Beijing Hosp, Inst Geriatr Med, Natl Ctr Clin Labs, Beijing, Peoples R China
Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Clin Labs, Beijing, Peoples R China
Beijing Hosp, Beijing Engn Res Ctr, Lab Med, Beijing, Peoples R ChinaChinese Acad Med Sci, Beijing Hosp, Inst Geriatr Med, Natl Ctr Clin Labs, Beijing, Peoples R China
Hou, Hanjing
Zhang, Rui
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机构:
Chinese Acad Med Sci, Beijing Hosp, Inst Geriatr Med, Natl Ctr Clin Labs, Beijing, Peoples R China
Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Clin Labs, Beijing, Peoples R China
Beijing Hosp, Beijing Engn Res Ctr, Lab Med, Beijing, Peoples R China
Beijing Hosp, Natl Ctr Clin Labs, 1 Dahua Rd,Dongdan, Beijing 100730, Peoples R ChinaChinese Acad Med Sci, Beijing Hosp, Inst Geriatr Med, Natl Ctr Clin Labs, Beijing, Peoples R China
Zhang, Rui
Li, Jinming
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机构:
Chinese Acad Med Sci, Beijing Hosp, Inst Geriatr Med, Natl Ctr Clin Labs, Beijing, Peoples R China
Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Clin Labs, Beijing, Peoples R China
Beijing Hosp, Beijing Engn Res Ctr, Lab Med, Beijing, Peoples R China
Beijing Hosp, Natl Ctr Clin Labs, 1 Dahua Rd,Dongdan, Beijing 100730, Peoples R ChinaChinese Acad Med Sci, Beijing Hosp, Inst Geriatr Med, Natl Ctr Clin Labs, Beijing, Peoples R China
机构:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Pathol, 55 Fruit St, Boston, MA 02114 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Pathol, 55 Fruit St, Boston, MA 02114 USA
机构:
Hop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Lab Alphabio, F-13000 Marseille, FranceHop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Halfon, Philippe
Penaranda, Guillaume
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机构:
Lab Alphabio, F-13000 Marseille, FranceHop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Penaranda, Guillaume
Ringwald, Dan
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DEEPA, F-94130 Nogent, FranceHop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Ringwald, Dan
Retornaz, Frederique
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机构:Hop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Retornaz, Frederique
Boissel, Nicolas
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机构:
Hop St Louis, AP HP, Serv Hematol, Paris, FranceHop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Boissel, Nicolas
Bodard, Sylvain
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机构:
Univ Paris Cite, F-75006 Paris, France
Hop Univ Necker Enfants Malad, AP HP, Serv Imagerie Adulte, F-75015 Paris, France
Sorbonne Univ, CNRS, INSERM, Lab Imagerie Biomed, F-75006 Paris, FranceHop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Bodard, Sylvain
Feryn, Jean Marc
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机构:Hop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
Feryn, Jean Marc
Bensoussan, David
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机构:
Ctr Hosp, Serv Chirurg Vasc, Ave Tamaris, F-13100 Aix En Provence, FranceHop Europeen, Pole Med Interne & Malad Infect, F-13000 Marseille, France
机构:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USA
Dimitriadis, Irene
Zaninovic, Nikica
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机构:
Weill Cornell Med, Ronald O Perelman & Claudia Cohen Ctr Reprod Med, New York, NY USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USA
Zaninovic, Nikica
Chavez Badiola, Alejandro
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机构:
New Hope Fertil Ctr, Av Prado Norte 135, Mexico City, DF, Mexico
IVF 2 0 LTD, 1 Liverpool Rd, Maghull, Merseyside, England
Univ Kent, Sch Biosci, Canterbury, Kent, EnglandHarvard Med Sch, Massachusetts Gen Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USA
Chavez Badiola, Alejandro
Bormann, Charles L.
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机构:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USA
机构:
Univ Pretoria, Dept Chem Pathol, Pretoria, South Africa
Natl Hlth Lab Serv, Pretoria, South AfricaUniv Pretoria, Dept Chem Pathol, Pretoria, South Africa
机构:
UTHealth, Sch Biomed Informat, Houston, TX USA
Tsinghua Univ, Dept Math Sci, Beijing, Peoples R ChinaUTHealth, Sch Biomed Informat, Houston, TX USA
Yu, Lishan
Li, Linda
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机构:
UTHealth, McGovern Med Sch, Dept Pediat Surg, Houston, TX USAUTHealth, Sch Biomed Informat, Houston, TX USA
Li, Linda
Bernstam, Elmer
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机构:
UTHealth, Sch Biomed Informat, Houston, TX USA
UTHealth, McGovern Med Sch, Div Gen Internal Med, Houston, TX USAUTHealth, Sch Biomed Informat, Houston, TX USA