Antibacterial Drug Release Electrochemically Stimulated by the Presence of Bacterial Cells - Theranostic Approach

被引：26

作者：

Gamella, Maria ^{[1
,2
]}

Guz, Nataliia ^{[1
]}

Mailloux, Shay ^{[1
]}

Pingarron, Jose M. ^{[2
]}

Katz, Evgeny ^{[1
]}

机构：

[1] Clarkson Univ, Dept Chem & Biomol Sci, Potsdam, NY 13699 USA

[2] Univ Complutense Madrid, Dept Analyt Chem, E-28040 Madrid, Spain

来源：

ELECTROANALYSIS | 2014年 / 26卷 / 12期

基金：

美国国家科学基金会;

关键词：

Bacteria detection; Modified electrodes; Sense-and-Treat; Alginate; Drug release; FOODBORNE PATHOGENIC BACTERIA; BIOFUEL CELLS; PYRROLOQUINOLINE QUINONE; MODEL SYSTEM; BIOSENSORS; LOGIC; MICROORGANISMS; GENOSENSOR; MONOLAYER; OXIDATION;

D O I：

10.1002/elan.201400473

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A modified electrode with bioaffinity to E. coli bacterial cells was used to detect bacteria presence on its surface and to produce an electrical signal triggering antibacterial drug release from another coupled electrode. The Sense-and-Treat system was realized in two different versions and suggested as the first step to future theranostic applications where bacteria presence results in automatic antibacterial treatment.

引用

页码：2552 / 2557

页数：6

共 28 条

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