Intermittent claudication - atypical presentation, diagnosis and treatment

被引：4
|
作者：
Taylor, I [1 ]
Dennett, X
Nicholls, K
Tubridy, N
机构：
[1] Royal Melbourne Hosp, Dept Neuropathol, Parkville, Vic 3050, Australia
[2] Royal Melbourne Hosp, Dept Neurol, Parkville, Vic 3050, Australia
[3] Royal Melbourne Hosp, Dept Nephrol, Parkville, Vic 3050, Australia
来源：
JOURNAL OF CLINICAL NEUROSCIENCE | 2004年 / 11卷 / 07期
关键词：
muscle biopsy; claudication; glycosphingolipid; microvascular; Fabry disease;
D O I：
10.1016/j.jocn.2004.02.002
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A unique case of a man with Fabry's disease and associated small vessel vasculopathy manifesting as recurrent episodes of intermittent claudication is described. The case highlights the concept that microvascular involvement due to local accumulation of glycosphingolipid in the smooth muscle fibres of vessel walls may be responsible for claudicant symptoms in such patients rather than the more classical macrovascular insufficiency. (C) 2004 Elsevier Ltd. All rights reserved.
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页码：783 / 785
页数：3
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