Synthesis and Studies of Novel Optically Active Schiff's Base Derivatives and their Antimicrobial Activities

被引:16
|
作者
Patel, Ishwar J. [1 ]
Parmar, Shailesh J. [1 ]
机构
[1] Veer Narmad S Gujarat Univ, SIR PT Sarvajanik Coll Sci, Dept Chem, Surat 395017, Gujarat, India
关键词
Schiff's base; Optically active; Chiral; Spectral studies; Specific optical rotation; Antibacterial activity and Antifungal activity; COMPLEXES;
D O I
10.1155/2010/956242
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Several new Schiff's base derivatives were prepared by condensing various substituted benzaldehyde with 1-(4-aminophenyl)-2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]-1-piperazinyl} ethanone in presence of acid catalyst under reflux condition. All the compounds were characterized by elemental analysis and spectral studies. The newly synthesized compounds were evaluated for their antibacterial and antifungal activity.
引用
收藏
页码:617 / 623
页数:7
相关论文
共 50 条
  • [1] Synthesis and Antimicrobial Activities of Some New Synthesized Imide and Schiff's Base Derivatives
    Sabry, Nermien M.
    Flefel, Eman M.
    Al-Omar, Mohamed A.
    Amr, Abd El-Galil E.
    [J]. JOURNAL OF CHEMISTRY, 2013, 2013
  • [2] Synthesis, antimicrobial evaluation and docking studies of some novel quinazolinone Schiff base derivatives
    Nasab, Rezvan Rezaee
    Mansourian, Mahboubeh
    Hassanzadeh, Farshid
    [J]. RESEARCH IN PHARMACEUTICAL SCIENCES, 2018, 13 (03) : 213 - 221
  • [3] Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
    Azab, Mohamed E.
    Rizk, Sameh A.
    Amr, Abd El-Galil E.
    [J]. MOLECULES, 2015, 20 (10): : 18201 - 18218
  • [4] Synthesis, Structure and Biological Activities of Novel Furanosyl Schiff Base Derivatives
    Yan, Lin
    Liu, Fengwu
    Liu, Hongmin
    [J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2011, 31 (10) : 1639 - 1642
  • [5] Schiff Base Mediated Synthesis of Novel Imidazolidine-4-One Derivatives for Potential Antimicrobial and Anthelmintic Activities
    Chilamakuru, Naresh Babu
    Singirisetty, Triveni
    Bodapati, Anoop
    Kallam, Sudha Divya Madhuri
    Nelson, Vinod Kumar
    Suryadevara, Punna Rao
    Thangaswamy, Selvankumar
    [J]. Luminescence, 2024, 39 (11)
  • [6] Novel Polyhydroquinoline-Hydrazide-Linked Schiff's Base Derivatives: Multistep Synthesis, Antimicrobial, and Calcium-Channel-Blocking Activities
    Zainab
    Yu, Haitao
    Rehman, Najeeb Ur
    Ali, Mumtaz
    Alam, Aftab
    Latif, Abdul
    Shahab, Nazish
    Khan, Irfan Amir
    Shah, Abdul Jabbar
    Khan, Momin
    Al-Ghafri, Ahmed
    Al-Harrasi, Ahmed
    Ahmad, Manzoor
    [J]. ANTIBIOTICS-BASEL, 2022, 11 (11):
  • [7] Antimicrobial activities of some novel Schiff base complexes
    Khan, Jamil
    Farooq, Rubina
    Farooq, Ather
    Khan, Abdur Rehman
    Mahmood, Qaisar
    Rashid, Rehana
    Haseeb, Muhammad
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [8] A Brief Review on Schiff Base, Synthesis, and Their Antimicrobial Activities
    Ruaa M. Dhedan
    Sanaa A. Alsahib
    Rana Abid Ali
    [J]. Russian Journal of Bioorganic Chemistry, 2023, 49 : S31 - S52
  • [9] A Brief Review on Schiff Base, Synthesis, and Their Antimicrobial Activities
    Dhedan, Ruaa M.
    Alsahib, Sanaa A.
    Ali, Rana Abid
    [J]. RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2023, 49 (SUPPL 1) : S31 - S52
  • [10] Novel Mannich Base Derivatives: Synthesis, Characterization, Antimicrobial and Antioxidant Activities
    Kotan, Gul
    [J]. LETTERS IN ORGANIC CHEMISTRY, 2021, 18 (10) : 830 - 841