Recent Progress of Microfluidics in Translational Applications

被引:27
|
作者
Liu, Zongbin [1 ,2 ]
Han, Xin [1 ,2 ]
Qin, Lidong [1 ,2 ,3 ]
机构
[1] Houston Methodist Res Inst, Dept Nanomed, Houston, TX 77030 USA
[2] Cornell Univ, Dept Cell & Dev Biol, Weill Med Coll, New York, NY 10065 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA
关键词
cellular analysis; chip-based material delivery; microfluidics; molecular analysis; organ-on-a-chip; CIRCULATING TUMOR-CELLS; BAR-CHART CHIP; ON-A-CHIP; SINGLE CELLS; LABEL-FREE; CANCER-PATIENTS; BREAST-CANCER; STEM-CELLS; RNA-SEQ; CAPTURE;
D O I
10.1002/adhm.201600009
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed.
引用
收藏
页码:871 / 888
页数:18
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