Psychological interventions to prevent relapse in anxiety and depression: A systematic review and meta-analysis

被引:3
|
作者
Krijnen-de Bruin, Esther [1 ,2 ,3 ]
Scholten, Willemijn [1 ,2 ]
Muntingh, Anna [1 ,2 ]
Maarsingh, Otto [4 ]
van Meijel, Berno [1 ,3 ,5 ]
van Straten, Annemieke [6 ]
Batelaan, Neeltje [1 ,2 ]
机构
[1] Vrije Univ, Amsterdam Publ Hlth Res Inst, Amsterdam UMC, Psychiat, Amsterdam, Netherlands
[2] GGZ Geest Specialised Mental Hlth Care, Amsterdam, Netherlands
[3] Inholland Univ Appl Sci, Hlth Sports & Welf Cluster Nursing, Amsterdam, Netherlands
[4] Vrije Univ, Amsterdam Publ Hlth Res Inst, Gen Practice & Elderly Care Med, Amsterdam UMC, Amsterdam, Netherlands
[5] Parnassia Acad, Parnassia Psychiat Inst, The Hague, Netherlands
[6] Vrije Univ, Amsterdam Publ Hlth Res Inst, Clin Neuro & Dev Psychol, Amsterdam UMC, Amsterdam, Netherlands
来源
PLOS ONE | 2022年 / 17卷 / 08期
关键词
COGNITIVE-BEHAVIORAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; RECURRENT DEPRESSION; FOLLOW-UP; MAJOR DEPRESSION; PRIMARY-CARE; PSYCHIATRIC-CONSULTATION; SEQUENTIAL INTEGRATION; MAINTENANCE TREATMENT; RESIDUAL DEPRESSION;
D O I
10.1371/journal.pone.0272200
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
ObjectivesThe aim of this review is to establish the effectiveness of psychological relapse prevention interventions, as stand-alone interventions and in combination with maintenance antidepressant treatment (M-ADM) or antidepressant medication (ADM) discontinuation for patients with remitted anxiety disorders or major depressive disorders (MDD).MethodsA systematic review and a meta-analysis were conducted. A literature search was conducted in PubMed, PsycINFO and Embase for randomised controlled trials (RCTs) comparing psychological relapse prevention interventions to treatment as usual (TAU), with the proportion of relapse/recurrence and/or time to relapse/recurrence as outcome measure.ResultsThirty-six RCTs were included. During a 24-month period, psychological interventions significantly reduced risk of relapse/recurrence for patients with remitted MDD (RR 0.76, 95% CI: 0.68-0.86, p < 0.001). This effect persisted with longer follow-up periods, although these results were less robust. Also, psychological interventions combined with M-ADM significantly reduced relapse during a 24-month period (RR 0.76, 95% CI: 0.62-0.94, p = 0.010), but this effect was not significant for longer follow-up periods. No meta-analysis could be performed on relapse prevention in anxiety disorders, as only two studies focused on relapse prevention in anxiety disorders.ConclusionsIn patients with remitted MDD, psychological relapse prevention interventions substantially reduce risk of relapse/recurrence. It is recommended to offer these interventions to remitted MDD patients. Studies on anxiety disorders are needed.Systematic review registration numberPROSPERO 2018: .
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页数:20
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