Comparison of tumor mutational burden (TMB) in PBRM1/BAP1-based subsets of advanced renal cell carcinoma (aRCC).

被引：1
|
作者：
Pal, Sumanta K.
Madison, Russell
Chung, Jon
Agarwal, Neeraj
Bergerot, Paulo Gustavo
Bosse, Dominick
Sokol, Ethan
Hartmaier, Ryan James
Miller, Vincent A.
Ross, Jeffrey S.
Choueiri, Toni K.
Ali, Siraj Mahamed
机构：
[1] City Hope Comprehens Canc Ctr, Duarte, CA USA
[2] Fdn Med Inc, Cambridge, MA USA
[3] Huntsman Canc Hosp, Salt Lake City, UT USA
[4] Fed Univ Sao Paulo UNIFESP, Sao Paulo, Brazil
[5] Ottawa Hosp Canc Ctr, Ottawa, ON, Canada
[6] Harvard Med Sch, Brigham & Womens Hosp, Dana Farber Canc Inst, Boston, MA USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2018年 / 36卷 / 06期
关键词：
D O I：
10.1200/JCO.2018.36.6_suppl.634
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
634
引用
收藏
页数：1
相关论文
共 50 条
  • [1] PBRM1 and BAP1 expression in renal cell carcinoma
    Kuthi, L.
    Fallmann, E.
    Jenei, A.
    Posfai, B.
    Maraz, A.
    [J]. VIRCHOWS ARCHIV, 2018, 473 : S44 - S44
  • [2] PBRM1 and BAP1 as Novel Targets for Renal Cell Carcinoma
    Brugarolas, James
    [J]. CANCER JOURNAL, 2013, 19 (04): : 324 - 332
  • [3] Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade
    Gu, Yi-Feng
    Cohn, Shannon
    Christie, Alana
    McKenzie, Tiffani
    Wolff, Nicholas
    Do, Quyen N.
    Madhuranthakam, Ananth J.
    Pedrosa, Ivan
    Wang, Tao
    Dey, Anwesha
    Busslinger, Meinrad
    Xie, Xian-Jin
    Hammer, Robert E.
    Mckay, Renee M.
    Kapur, Payal
    Brugarolas, James
    [J]. CANCER DISCOVERY, 2017, 7 (08) : 900 - 917
  • [4] BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor
    Jeanette E. Eckel-Passow
    Daniel J. Serie
    John C. Cheville
    Thai H. Ho
    Payal Kapur
    James Brugarolas
    R. Houston Thompson
    Bradley C. Leibovich
    Eugene D. Kwon
    Richard W. Joseph
    Alexander S. Parker
    [J]. BMC Urology, 17
  • [5] Mutational Analysis of PBRM1 and Significance of PBRM1 Mutation in Anti-PD-1 Immunotherapy of Clear Cell Renal Cell Carcinoma
    Aili, Abudureyimujiang
    Wen, Jie
    Xue, Lixiang
    Wang, Junjie
    [J]. FRONTIERS IN ONCOLOGY, 2021, 11
  • [6] BAP1 and PBRM1 in metastatic clear cell renal cell carcinoma: tumor heterogeneity and concordance with paired primary tumor
    Eckel-Passow, Jeanette E.
    Serie, Daniel J.
    Cheville, John C.
    Ho, Thai H.
    Kapur, Payal
    Brugarolas, James
    Thompson, R. Houston
    Leibovich, Bradley C.
    Kwon, Eugene D.
    Joseph, Richard W.
    Parker, Alexander S.
    [J]. BMC UROLOGY, 2017, 17 : 1 - 7
  • [7] Clear Cell Renal Cell Carcinoma Subtypes Identified by BAP1 and PBRM1 Expression
    Joseph, Richard W.
    Kapur, Payal
    Serie, Daniel J.
    Parasramka, Mansi
    Ho, Thai H.
    Cheville, John C.
    Frenkel, Eugene
    Parker, Alexander S.
    Brugarolas, James
    [J]. JOURNAL OF UROLOGY, 2016, 195 (01): : 180 - 187
  • [8] Bap1 and Pbrm1: Determinants of Tumor Grade and mTOR Activation in VHL-Deficient Mouse Models of Renal Cell Carcinoma
    Leung, Janet Y.
    Kim, William Y.
    [J]. CANCER DISCOVERY, 2017, 7 (08) : 802 - 804
  • [9] A germline mutation in PBRM1 predisposes to renal cell carcinoma
    Benusiglio, Patrick R.
    Couve, Sophie
    Gilbert-Dussardier, Brigitte
    Deveaux, Sophie
    Le Jeune, Helene
    Da Costa, Melanie
    Fromont, Gaelle
    Memeteau, Francoise
    Yacoub, Mokrane
    Coupier, Isabelle
    Leroux, Dominique
    Mejean, Arnaud
    Escudier, Bernard
    Giraud, Sophie
    Gimenez-Roqueplo, Anne-Paule
    Blondel, Christophe
    Frouin, Eric
    Teh, Bin T.
    Ferlicot, Sophie
    Bressac-de Paillerets, Brigitte
    Richard, Stephane
    Gad, Sophie
    [J]. JOURNAL OF MEDICAL GENETICS, 2015, 52 (06) : 426 - 430
  • [10] The role of PBRM1 as tumor suppressor gene in renal cell carcinomas
    Jandrig, Burkhard
    Ikromov, Odiljon
    Hoegner, Anica
    Wendler, Johann J.
    Schostak, Martin
    Krause, Hans
    [J]. CANCER RESEARCH, 2014, 74 (19)
12345