Lymphatic Dysregulation in Patients With Heart Failure JACC Review Topic of the Week

被引：40

作者：

Fudim, Marat ^{[1
,2
]}

Salah, Husam M. ^{[3
]}

Sathananthan, Janarthanan ^{[4
,5
]}

Bernier, Mathieu ^{[6
]}

Pabon-Ramos, Waleska ^{[7
]}

Schwartz, Robert S. ^{[8
]}

Rodes-Cabau, Josep ^{[6
,9
]}

Cote, Francois ^{[10
]}

Khalifa, Abubaker ^{[11
]}

Virani, Sean A. ^{[4
,5
]}

Patel, Manesh R. ^{[1
,2
]}

机构：

[1] Duke Univ, Med Ctr, Dept Med, Div Cardiol, Durham, NC USA

[2] Duke Clin Res Inst, Durham, NC USA

[3] Univ Arkansas Med Sci, Dept Med, Little Rock, AR 72205 USA

[4] Univ British Columbia, Ctr Cardiovasc Innovat, Vancouver, BC, Canada

[5] Univ British Columbia, Div Cardiol, Vancouver, BC, Canada

[6] Laval Univ, Quebec Heart & Lung Inst, Quebec City, PQ, Canada

[7] Duke Univ, Med Ctr, Dept Radiol, Div Intervent Radiol, Durham, NC USA

[8] Minneapolis Heart Inst, Minneapolis, MN USA

[9] Hosp Clin Barcelona, Barcelona, Spain

[10] Laval Univ, CHU Quebec, Intervent Radiol Dept, Quebec City, PQ, Canada

[11] McMaster Univ, Joseph Brant Hosp, Dept Med, Hamilton, ON, Canada

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2021年 / 78卷 / 01期

关键词：

SYSTEMIC VENOUS-PRESSURE; THORACIC-DUCT; MYOCARDIAL EDEMA; RENAL-FUNCTION; LYMPHANGIOGRAPHY; EMBOLIZATION; ELEVATION; FLOW; INFLAMMATION; CONGESTION;

D O I：

10.1016/j.jacc.2021.04.090

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The lymphatic system is an integral part of the circulatory system and plays an important rote in the volume homeostasis of the human body. The complex anatomy and physiology paired with a tack of simple diagnostic toots to study the lymphatic system have led to an underappreciation of the contribution of the lymphatic system to acute and chronic heart failure (HF). Herein, we discuss the physiological rote of the lymphatic system in volume management and the evidence demonstrating the dysregulation of the lymphatic system in HF. Further, we discuss the opportunity to target the lymphatic system in the management of HF and different potential approaches to accessing the lymphatic system. (C) 2021 by the American College of Cardiology Foundation.

引用

页码：66 / 76

页数：11

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