Modeling of interstitial fluid movement in soft tissue under negative pressure - relevance to treatment of tissue swelling

被引：7

作者：

Iivarinen, Jarkko T. ^{[1
,2
]}

Korhonen, Rami K. ^{[1
]}

Jurvelin, Jukka S. ^{[1
]}

机构：

[1] Univ Eastern Finland, Dept Appl Phys, Kuopio, Finland

[2] Kuopio Univ Hosp, Dept Phys & Rehabil Med, SF-70210 Kuopio, Finland

来源：

COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING | 2016年 / 19卷 / 10期

基金：

芬兰科学院;

关键词：

suction treatment; Skin; fluid; edema; finite element analysis; SKIN IN-VIVO; FINITE-ELEMENT MODEL; MECHANICAL-PROPERTIES; VISCOELASTIC PROPERTIES; COMPUTATIONAL ANALYSIS; ARTICULAR-CARTILAGE; SKELETAL-MUSCLE; BREAST-CANCER; BEHAVIOR; INDENTATION;

D O I：

10.1080/10255842.2015.1101073

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Exact physiological mechanisms behind the potential positive treatment effects of pathological tissue swelling (edema), such as increased interstitial fluid flow, are poorly understood. Finite-element model was created and the model response was matched with the deformation data from the negative pressure (suction) measurements in human (N=11) forearm. Two experimental suction protocols were simulated to evaluate their impact on interstitial fluid flow in soft tissues. Simulated continuous suction was up to 27 times more efficient in fluid transportation compared to the cyclic suction. The continuous suction that transports the interstitial fluid effectively may help to decrease soft tissue edema.

引用

页码：1089 / 1098

页数：10

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