Multi-beam optical coherence tomography for microvascular imaging of human skin in vivo

被引：2
|
作者：
Chen, Chaoliang [1 ,2 ]
Cheng, Kyle H. Y. [2 ]
Jakubovic, Raphael [4 ]
Jivraj, Jamil [2 ]
Ramjist, Joel [2 ]
Deorajh, Ryan [2 ]
Gao, Wanrong [1 ]
Yang, Victor X. D. [2 ,3 ,5 ]
机构：
[1] Nanjing Univ Sci & Technol, Dept Opt Engn, Nanjing, Jiangsu, Peoples R China
[2] Ryerson Univ, Dept Elect & Comp Engn, Biophoton & Bioengn Lab, Toronto, ON, Canada
[3] Sunnybrook Hlth Sci Ctr, Div Neurosurg, Toronto, ON, Canada
[4] Ryerson Univ, Dept Biomed Phys, Toronto, ON, Canada
[5] Univ Toronto, Fac Med, Div Neurosurg, Toronto, ON, Canada
来源：
THREE-DIMENSIONAL AND MULTIDIMENSIONAL MICROSCOPY: IMAGE ACQUISITION AND PROCESSING XXIV | 2017年 / 10070卷
基金：
中国国家自然科学基金; 加拿大创新基金会; 加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词：
Optical coherence tomography; medical and biological imaging; tomographic image processing; MICROCIRCULATION; FLOW;
D O I：
10.1117/12.2250739
中图分类号：
TH742 [显微镜];
学科分类号：
摘要：
In this paper, a multi-beam optical coherence tomography (OCT) was used to reconstruct the microvascular image of human skin in vivo with phase resolved Doppler OCT (PRDOCT), phase resolved Doppler variance (PRDV) and speckle variance OCT (svOCT), in which the blood flow image was calculated by averaging the four blood flow images obtained by the four beams. In PRDOCT method, it is difficult to detect the blood flow perpendicular to optical axis of the probe beam for single beam OCT, but the multi-beam scanning method can solve this because the input angles of the four probe beams are slightly different from each other. The proposed method can further improve the signal-to-noise ratio (SNR) of the blood flow signals extracted by the three methods mentioned above.
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页数：8
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