Total syntheses of the chlorinated β-carboline alkaloids bauerine A, B, and C

被引：16
|
作者：
Pohl, Berthold [1 ]
Luchterhandt, Thomas [1 ]
Bracher, Franz [1 ]
机构：
[1] Univ Munich, Ctr Drug Res, Dept Pharm, D-81377 Munich, Germany
来源：
SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 7-9期
关键词：
alkaloids; bauerine; cyclizations; dehydrogenations; 1-oxo-beta-carbolines;
D O I：
10.1080/00397910701226228
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first total synthesis of the chlorinated 1-oxo-/beta-carboline alkaloid bauerine C based on a Japp-Klingemann reaction is reported. An intermediate of this synthesis was converted to the fully aromatic beta-carboline bauerine B, and the related alkaloid bauerine A was prepared in an analogous manner.
引用
收藏
页码：1273 / 1280
页数：8
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