Severe amyotrophic lateral sclerosis (ALS) patients cannot move their muscles, and sometimes even respiratory muscles are affected so that they are obliged to mount artificial respiratory devices, Of course, the patients of this severity sb;age cannot speak., The motor function of the patients remained in eye movement. The communication mean for those patients is the eye movement. They have used a transparent alphabetic table, But it is cumbersome for both the patients and help givers, and it its also time consuming, A computer mouse whose cursor can be controlled with eye movement has been developed, The eye movement is detected by electro oculography, and its click is realized by a voluntary blinking. By pointing a cursor to a specified letter on an alphabetic table on a monitor screen, a patient can describe his/her intention. It is found to be useful for severe ALS patients.