Structure-based design of irreversible human rhinovirus 3C protease inhibitors.

被引:0
|
作者
Dragovich, PS [1 ]
Webber, SE [1 ]
Babine, RE [1 ]
Fuhrman, SA [1 ]
Patick, AK [1 ]
Matthews, DA [1 ]
Reich, SH [1 ]
Prins, TJ [1 ]
Marakovits, JT [1 ]
Littlefield, ES [1 ]
Zhou, R [1 ]
Tikhe, J [1 ]
Ford, CE [1 ]
Wallace, MB [1 ]
Bleckman, TM [1 ]
Meador, JW [1 ]
Ferre, RA [1 ]
Brown, EL [1 ]
Binford, SL [1 ]
DeLisle, DM [1 ]
Worland, ST [1 ]
机构
[1] Agouron Pharmaceut Inc, San Diego, CA 92121 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
011-MEDI
引用
收藏
页码:U863 / U863
页数:1
相关论文
共 50 条
  • [1] Structure-based design of irreversible peptidyl and peptidomimetic human rhinovirus 3C protease inhibitors.
    Dragovich, PS
    Webber, SE
    Fuhrman, SA
    Patick, AK
    Matthews, DA
    Lee, CA
    Tuntland, T
    Prins, TJ
    Marakovits, JT
    Zhou, R
    Tikhe, J
    Ford, CE
    Meador, JW
    Harr, JEV
    Kosa, MB
    Ferre, RA
    Brown, EL
    Binford, SL
    DeLisle, DM
    Worland, ST
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U1233 - U1233
  • [2] Structure-based design of irreversible, peptidomimetic human rhinovirus 3C protease inhibitors
    Dragovich, PS
    Webber, SE
    Fuhrman, SA
    Patick, AK
    Matthews, DA
    Prins, TJ
    Zhou, R
    Marakovits, JT
    Ford, CE
    Meador, JW
    Ferre, RA
    Worland, ST
    MEDICINAL CHEMISTRY INTO THE MILLENNIUM, 2001, (264): : 223 - 232
  • [3] Structure-based design of ketone-containing human rhinovirus 3C protease inhibitors.
    Dragovich, PS
    Zhou, R
    Webber, SE
    Prins, TJ
    Kwok, AK
    Okano, K
    Fuhrman, SA
    Zalman, LS
    Maldonado, FG
    Brown, EL
    Patick, AK
    Matthews, DA
    Ford, CE
    Brothers, MA
    Meadow, JW
    Ferre, RA
    Binford, SL
    Worland, ST
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U3 - U3
  • [4] Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors
    Namoto, Kenji
    Sirockin, Finton
    Sellner, Holger
    Wiesmann, Christian
    Villard, Frederic
    Moreau, Robert J.
    Valeur, Eric
    Paulding, Stephanie C.
    Schleeger, Simone
    Schipp, Kathrin
    Loup, Joachim
    Andrews, Lori
    Swale, Ryann
    Robinson, Michael
    Farady, Christopher J.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (05) : 906 - 909
  • [5] Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies
    Dragovich, PS
    Webber, SE
    Babine, RE
    Fuhrman, SA
    Patick, AK
    Matthews, DA
    Reich, SH
    Marakovits, JT
    Prins, TJ
    Zhou, R
    Tikhe, J
    Littlefield, ES
    Bleckman, TM
    Wallace, MB
    Little, TL
    Ford, CE
    Meador, JW
    Ferre, RA
    Brown, EL
    Binford, SL
    DeLisle, DM
    Worland, ST
    JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (15) : 2819 - 2834
  • [6] Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease
    Johnson, TO
    Hua, Y
    Luu, HT
    Brown, EL
    Chan, F
    Chu, SS
    Dragovich, PS
    Eastman, BW
    Ferre, RA
    Fuhrman, SA
    Hendrickson, TF
    Maldonado, FC
    Matthews, DA
    Meador, JW
    Patick, AK
    Reich, SH
    Skalitzky, DJ
    Worland, ST
    Yang, M
    Zalman, LS
    JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (10) : 2016 - 2023
  • [7] Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies
    Dragovich, PS
    Webber, SE
    Babine, RE
    Fuhrman, SA
    Patick, AK
    Matthews, DA
    Lee, CA
    Reich, SH
    Prins, TJ
    Marakovits, JT
    Littlefield, ES
    Zhou, R
    Tikhe, J
    Ford, CE
    Wallace, MB
    Meador, JW
    Ferre, RA
    Brown, EL
    Binford, SL
    Harr, JEV
    DeLisle, DM
    Worland, ST
    JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (15) : 2806 - 2818
  • [8] Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure - Activity studies of ketomethylene-containing peptidomimetics
    Dragovich, PS
    Prins, TJ
    Zhou, R
    Fuhrman, SA
    Patick, AK
    Matthews, DA
    Ford, CE
    Meador, JW
    Ferre, RA
    Worland, ST
    JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (07) : 1203 - 1212
  • [9] Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors
    Webber, SE
    Marakovits, JT
    Dragovich, PS
    Prins, TJ
    Zhou, R
    Fuhrman, SA
    Patick, AK
    Matthews, DA
    Lee, CA
    Srinivasan, B
    Moran, T
    Ford, CE
    Brothers, MA
    Harr, JEV
    Meador, JW
    Ferre, RA
    Worland, ST
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (20) : 2683 - 2686
  • [10] Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors
    Dragovich, PS
    Zhou, R
    Webber, SE
    Prins, TJ
    Kwok, AK
    Okano, K
    Fuhrman, SA
    Zalman, LS
    Maldonado, FC
    Brown, EL
    Meador, JW
    Patick, AK
    Ford, CE
    Brothers, MA
    Binford, SL
    Matthews, DA
    Ferre, RA
    Worland, ST
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (01) : 45 - 48