Crosstalk of Multi-Omics Platforms with Plants of Therapeutic Importance

被引:18
|
作者
Pandita, Deepu [1 ]
Pandita, Anu [2 ]
Wani, Shabir Hussain [3 ]
Abdelmohsen, Shaimaa A. M. [4 ]
Alyousef, Haifa A. [4 ]
Abdelbacki, Ashraf M. M. [5 ]
Al-Yafrasi, Mohamed A. [6 ]
Al-Mana, Fahed A. [6 ]
Elansary, Hosam O. [6 ]
机构
[1] Govt Dept, Sch Educ, Jammu 180001, Jammu & Kashmir, India
[2] Vatsalya Clin, Delhi 110051, India
[3] Sher E Kashmir Univ Agr Sci & Technol Kashmir, Mt Res Ctr Field Crops, Khudwani Anantnag 192101, Jammu & Kashmir, India
[4] Princess Nourah bint Abdulrahman Univ, Phys Dept, Fac Sci, Riyadh 84428, Saudi Arabia
[5] King Saud Univ, Appl Studies & Community Serv Coll, Riyadh 11451, Saudi Arabia
[6] King Saud Univ, Plant Prod Dept, Coll Food & Agr Sci, Riyadh 11451, Saudi Arabia
关键词
medicinal plants; multi-omics platforms; genomics; transcriptomics; proteomics; metabolomics; NATURALLY-OCCURRING IRIDOIDS; METABOLIC GENE CLUSTERS; GENOME PROVIDES INSIGHT; MEDICINAL-PLANTS; PROTEOMIC ANALYSIS; ANDROGRAPHIS-PANICULATA; FLAVONOID BIOSYNTHESIS; TRANSCRIPTOME ANALYSIS; MORPHINE BIOSYNTHESIS; ALKALOID BIOSYNTHESIS;
D O I
10.3390/cells10061296
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
From time immemorial, humans have exploited plants as a source of food and medicines. The World Health Organization (WHO) has recorded 21,000 plants with medicinal value out of 300,000 species available worldwide. The promising modern "multi-omics" platforms and tools have been proven as functional platforms able to endow us with comprehensive knowledge of the proteome, genome, transcriptome, and metabolome of medicinal plant systems so as to reveal the novel connected genetic (gene) pathways, proteins, regulator sequences and secondary metabolite (molecule) biosynthetic pathways of various drug and protein molecules from a variety of plants with therapeutic significance. This review paper endeavors to abridge the contemporary advancements in research areas of multi-omics and the information involved in decoding its prospective relevance to the utilization of plants with medicinal value in the present global scenario. The crosstalk of medicinal plants with genomics, transcriptomics, proteomics, and metabolomics approaches will be discussed.
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页数:23
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