Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours)

Progress in the diagnostics and therapy of gastro-entero-pancreatic (GEP) neuroendocrine neoplasms (NEN), results of new randomised clinical trials, and publication of the new guidelines by the European Neuroendocrine Tumour Society (ENETS) have led the Polish Network of Neuroendocrine Tumours to update its 2013 guidelines regarding on management of these neoplasms. This article presents the general recommendations for the management of NENs, developed by experts during the 3rd Round Table Conference - Diagnosis and therapy of gastro-entero-pancreatic neuroendocrine neoplasms: Polish recommendations in view of current European recommendations, which took place in December 2016 in Zelechow near Warsaw. Based on the extensive experience of the centres dealing with this type of neoplasms we believe that we have developed the optimal management system, for these patients which applies the most recent achievements and can be implemented effectively in Poland. These management guidelines have been arranged in the following order: gastric and duodenal NENs (including gastrinoma); pancreatic NENs; NENs of the small intestine and appendix, and colorectal NENs.