Impact of limited population diversity of genome-wide association studies

被引：78
|
作者：
Haga, Susanne B. [1 ,2 ]
机构：
[1] Duke Univ, Inst Genome Sci & Policy, Durham, NC 27708 USA
[2] Duke Univ, Sanford Sch Publ Policy, Durham, NC 27708 USA
来源：
GENETICS IN MEDICINE | 2010年 / 12卷 / 02期
关键词：
genome-wide association studies; race; disparities; AFRICAN-AMERICAN; CLINICAL-TRIALS; GENETIC RESEARCH; PUBLIC UNDERSTANDINGS; CANCER-RISK; FOLLOW-UP; PARTICIPATION; ATTITUDES; WOMEN; PHARMACOGENOMICS;
D O I：
10.1097/GIM.0b013e3181ca2bbf
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The article describes the limited population diversity of genome-wide association studies and its resulting impact on the development of commercial genetic tests with restricted applicability and usefulness to certain groups, potentially increasing existing disparities. To enable development of new clinical tools applicable to all groups, much more focus is needed to engage minority communities to enroll in genetics or genomic research studies and on investigators to reach out to underrepresented communities. Genet Med 2010:12(2):81-84.
引用
收藏
页码：81 / 84
页数：4
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