Emergence of macrolide resistant Streptococcus pyogenes strains in pediatric patients in France

被引：8
|
作者：
Mariani-Kurkdjian, P [1 ]
Doit, C
Deforche, D
Brahimi, N
Francois, M
Van den Abbeele, T
Bingen, E
机构：
[1] Hop Robert Debre, Microbiol Serv, Paris, France
[2] Hop Robert Debre, Serv ORL, Paris, France
来源：
PATHOLOGIE BIOLOGIE | 2004年 / 52卷 / 08期
关键词：
Streptococcus pyogenes; tonsillopharyngitis; macrolide;
D O I：
10.1016/j.patbio.2004.07.032
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
A total of 206 recent throat isolates of Streptococcus pyogenes collected between 2002 and 2004 from children were tested for their susceptibility to penicillin, amoxycillin, erythromycin, clarythromycin and clindamycin. The erythromycin resistant isolates were further studied for their genetic mechanism of resistance by means of PCR. In all, 14,5% of the strains were erythromycin resistant and 13.5 and 1% expressed the constitutive MLSB and M resistance phenotypes and harbored the ermB and mefA genes respectively. (C) 2004 Elsevier SAS. Tous droits reserves.
引用
收藏
页码：489 / 492
页数：4
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