RGH-188, a D3/D2 dopamine receptor partial agonist antipsychotic candidate with excellent brain availability and low EPS liability

被引：0

作者：

Gyertyan, Istvan ^{[1
]}

Kiss, Bela ^{[1
]}

Saghy, Katalin ^{[1
]}

Pasztor, Gabriella ^{[1
]}

Gemesi, Larisza I. ^{[1
]}

Kapas, Margit ^{[1
]}

Agai-Csongor, Eva ^{[1
]}

Domany, Gyorgy ^{[1
]}

Tihanyi, Karoly ^{[1
]}

Szombathelyi, Zsolt ^{[1
]}

机构：

[1] Pharmacol & Drug Safety Res, Budapest, Hungary

来源：

BIOLOGICAL PSYCHIATRY | 2007年 / 61卷 / 08期

关键词：

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

244

引用

页码：76S / 76S

页数：1

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[1] RGH-188, a d3/d2 dopamine receptor antagonist/partial agonist atypical antipsychotic candidate
Laszlovszky, I.
Kiss, B.
Gyertyan, I.
Meszaros, G. Pasztor
Seneca, N.
Schmidt, E.
Nemethy, Z. S.
Bugovics, G. Y.
Saghy, K.
Laszy, J.
Kapas, M.
Nemeth, G. Y.
Szombathelyi, Z. S.
EUROPEAN PSYCHIATRY, 2008, 23 : S163 - S163
[2] Favourable behavioural actions of RGH-188, a novel dopamine D3/D2 receptor antagonist/partial agonist antipsychotic candidate
Gyertyan, I.
Kiss, B.
Saghy, K.
Laszy, J.
Szabo, G.
Agai-Csongor, E.
Domany, G.
Tihanyi, K.
Szombathelyi, Z.
BEHAVIOURAL PHARMACOLOGY, 2007, 18 : S12 - S13
[3] Pharmacological profile of RGH-188, a novel dopamine D3/D2 receptor antagonist/partial agonist atypical antipsychotic
Gyertyan, I.
Kiss, B.
Saghy, K.
Laszlovszky, I.
Horvath, A.
Laszy, J.
Schmidt, E.
Szabo, G.
Domany, G.
Csongor, E. Agai
Tihanyi, K.
Szombathelyi, Z.
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2006, 16 : S432 - S432
[4] Dopamine 1321133 receptor occupancy of RGH-188, a D3/D2 antagonist/partial agonist antipsychotic, in healthy volunteers
Laszovszky, I.
Nemeth, G.
Meszaros, G. Pasztor
Kapas, M.
Brooks, D. J.
Pavese, N.
Szombathelyi, Z.
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2007, 17 : S455 - S455
[5] RGH-188, an atypical antipsychotic with dopamine D3/D2 antagonist/partial agonist properties:: In vitro characterisation
Kiss, B.
Laszlovszky, I.
Horvath, A.
Schmidt, E.
Bugovics, Gy.
Orosz, Sz.
Hornok, K.
Gyertyan, I.
Agai-Csongor, E.
Domany, Gy.
Tihanyi, K.
Szombathelyi, Zs.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S221 - S222
[6] Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile
Kiss, Bela
Horvath, Attila
Nemethy, Zsolt
Schmidt, Eva
Laszlovszky, Istvan
Bugovics, Gyula
Fazekas, Karoly
Hornok, Katalin
Orosz, Szabolcs
Gyertyan, Istvan
Agai-Csongor, Eva
Domany, Gyoergy
Tihanyi, Karoly
Adham, Nika
Szombathelyi, Zsolt
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2010, 333 (01): : 328 - 340
[7] RGH-188, an atypical antipsychotic with dopamine D3/D2 antagonist/partial agonist properties:: Neurochemical characterisation
Kiss, B.
Gyertyan, I.
Agai-Csongor, E.
Domany, Gy.
Tihanyi, K.
Szombathelyi, Zs.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S222 - S222
[8] RGH-188, an atypical antipsychotic with dopamine D3/D2 antagonist/partial agonist properties:: Behavioral characterisation
Gyertyan, I.
Kiss, B.
Saghy, K.
Laszy, J.
Szabo, Gy.
Agai-Csongor, E.
Domany, Gy.
Tihanyi, K.
Szombathelyi, Zs.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S222 - S222
[9] Pharmacokinetics of RGH-188, a novel dopamine D3/D2 antagonist/partial agonist atypical antipsychotic, in rats and dogs
Meszaros, G. Pasztor
Bolf, E. Terjeki
Gemesi, L.
Kapas, M.
Tihanyi, K.
Szombathelyi, Z.
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2008, 18 : S456 - S457
[10] Pharmacokinetics of RGH-188, a new dopamine D3/D2 antagonist/partial agonist atypical antipsychotic, in healthy subjects
Meszaros, G. Pasztor
Kapas, M.
Borsos, M.
Laszlovszky, I.
Nemeth, G.
Tihanyi, K.
Szombathelyi, Z.
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2007, 17 : S451 - S452

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