Waitlist mortality and transplant free survival in Hispanic patients listed for liver transplant using the UNOS database

被引:10
|
作者
Goyes, Daniela [1 ]
Danford, Christopher J. [1 ]
Nsubuga, John Paul [2 ]
Bonder, Alan [1 ]
机构
[1] Beth Israel Deaconess Med Ctr, Div Gastroenterol & Hepatol, Boston, MA 02215 USA
[2] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
关键词
Liver transplant; Ethnicity; Disparities; Hispanics; Share; 35; NONALCOHOLIC STEATOHEPATITIS; DISPARITIES; EXPRESSION; CIRRHOSIS; DISEASE; IMPACT; MODEL;
D O I
10.1016/j.aohep.2021.100304
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Introduction and objectives: After the implementation of "Share 35", several concerns arose such as the potential to increase travel distance, costs, and decreased liver availability. These elements could have a negative impact on waitlist outcomes among ethnic minorities. We aimed to determine waitlist survival after the implementation of the Share 35 policy in non-Hispanic white and Hispanic patients. Materials and methods: We identified non-Hispanic whites and Hispanics who were listed for liver transplantation from June 18th, 2013 to June 18, 2018. We excluded pediatric patients, patients with acute hepatic necrosis, re-transplants, multiorgan transplant, living donor, and exception cases. The primary outcome was death or removal from the waitlist due to clinical deterioration. We used competing risk analysis to compare waitlist survival between the two groups. Results: There were 23,340 non-Hispanic whites and 4938 Hispanics listed for transplant. On competing risk analysis, Hispanic patients had a higher risk of being removed from the waitlist for death or clinical deterioration compared to their counterpart (SHR 1.23, 95% CI 1.13-1.34; P < 0.001). Conclusion: After the implementation of Share 35, disparities are still present and continue to negatively impact outcomes in minority populations especially Hispanic patients. (c) 2021 Fundaci & oacute;n Cli & acute;nica M & eacute;dica Sur, A.C. Published by Elsevier Espan & tilde;a, S.L.U. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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页数:6
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