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- [9] Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (35) : 8950 - 8958