A tumor stem cell marker DCLK1 promotes hepatocellular carcinoma by regulating β-catenin, EMT and clonogenic properties of hepatocytes

被引：0
|
作者：
Ali, Naushad
Nguyen, Charles B.
Chandrakesan, Parthasarathy
May, Randal
Dhanasekaran, Danny
Bronze, Michael S.
Houchen, Courtney W.
机构：
来源：
CANCER RESEARCH | 2017年 / 77卷
关键词：
D O I：
10.1158/1538-7445.AM2017-3884
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3884
引用
收藏
页数：2
相关论文
共 50 条
  • [1] The tumor stem cell marker doublecortin-like kinase (DCLK1) activates inflammatory and carcinogenic signals in hepatocellular carcinoma
    Ali, Naushad
    Chandrakesan, Parthasarathy
    Nguyen, Charles B.
    Husain, Sanam
    Gillaspy, Allison F.
    Huycke, Mark
    Berry, William L.
    May, Randal
    Qu, Dongfeng
    Weygant, Nathaniel
    Sureban, Sripathi M.
    Dhanasekaran, Danny N.
    Houchen, Courtney W.
    CANCER RESEARCH, 2015, 75
  • [2] A putative stem cell marker, doublecortin-like kinase (DCLK1), is involved in the development of hepatocellular carcinoma
    Ali, Naushad
    CANCER RESEARCH, 2013, 73 (08)
  • [3] DCLK1 promotes hepatocellular carcinoma via atypical β-catenin-regulated signaling and immune suppression
    Ali, Naushad
    Chandrakesan, Parthasarathy
    Bronze, Michael S.
    Houchen, Courtney W.
    CANCER RESEARCH, 2019, 79 (13)
  • [4] DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma
    Lorenzo, Nevi
    Sabina, Di Matteo
    Guido, Carpino
    Grazia, Zizzari Ilaria
    Samira, Safarikia
    Valeria, Ambmsino
    Daniele, Costantini
    Diletta, Overi
    Antonella, Giancotti
    Marco, Monti
    Daniela, Bosco
    Valerio, De Peppo
    Andrea, Oddi
    Maria, De Rose Agostino
    Fabio, Melandro
    Consiglia, Bragazzi Maria
    Jessica, Faccioli
    Sara, Massironi
    Luca, Grazi Gian
    Benedetti, Panici Pierluigi
    Bartomeo, Berloco Paquale
    Felice, Giuliante
    Vincenzo, Cardinale
    Pietro, Invernizzi
    Giuseppina, Caretti
    Eugenio, Gaudio
    Domenico, Alvaro
    HEPATOLOGY, 2021, 73 (01) : 144 - 159
  • [5] Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism
    Sureban, Sripathi M.
    Madhoun, Mohammad F.
    May, Randal
    Qu, Dongfeng
    Ali, Naushad
    Fazili, Javid
    Weygant, Nathaniel
    Chandrakesan, Parthasarathy
    Ding, Kai
    Lightfoot, Stanley A.
    Houchen, Courtney W.
    ONCOTARGET, 2015, 6 (35) : 37200 - 37215
  • [6] DCLK1 is Overexpressed and Associated with Immune Cell Infiltration in Hepatocellular Carcinoma
    Velazquez-Enriquez, Juan Manuel
    Cerna, Renata
    Beltran-Ramirez, Olga
    Pina-Vazquez, Carolina
    Villa-Trevino, Saul
    Vasquez-Garzon, Veronica Rocio
    BIOCHEMICAL GENETICS, 2024, 62 (06) : 4280 - 4302
  • [7] DCLK1 promotes malignant progression of breast cancer by regulating Wnt/β-Catenin signaling pathway
    Wang, Y-L.
    Li, Y.
    Ma, Y-G.
    Wu, W-Y.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 (21) : 9489 - 9498
  • [8] DCLK1 is part of an EMT feedback loop and promotes colorectal cancer cell invasion and drug resistance
    Qu, Dongfeng
    Weygant, Nathaniel
    Berry, William L.
    May, Randal
    Chandrakesan, Parthasarathy
    Tomasek, James J.
    Sureban, Sripathi M.
    Houchen, Courtney
    Ge, Yang
    Yao, Jiannan
    An, Guangyu
    Bannerman-Menson, Edwin
    CANCER RESEARCH, 2017, 77
  • [9] Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment
    Cao, Zhiyun
    Weygant, Nathaniel
    Chandrakesan, Parthasarathy
    Houchen, Courtney W.
    Peng, Jun
    Qu, Dongfeng
    CANCERS, 2020, 12 (12) : 1 - 17
  • [10] High expression of the putative cancer stem cell marker, DCLK1, in rectal neuroendocrine tumors
    Ikezono, Yu
    Koga, Hironori
    Abe, Mitsuhiko
    Akiba, Jun
    Kawahara, Akihiko
    Yoshida, Takafumi
    Nakamura, Toru
    Iwamoto, Hideki
    Yano, Hirohisa
    Kage, Masayoshi
    Sata, Michio
    Tsuruta, Osamu
    Torimura, Takuji
    ONCOLOGY LETTERS, 2015, 10 (04) : 2015 - 2020
12345