Intracellular Silicon Chips in Living Cells

被引：29

作者：

Gomez-Martinez, Rodrigo ^{[1
]}

Vazquez, Patricia ^{[2
]}

Duch, Marta ^{[1
]}

Muriano, Alejandro ^{[3
]}

Pinacho, Daniel ^{[3
]}

Sanvicens, Nuria ^{[3
]}

Sanchez-Baeza, Francisco ^{[3
]}

Boya, Patricia ^{[2
]}

de la Rosa, Enrique J. ^{[2
]}

Esteve, Jaume ^{[1
]}

Suarez, Teresa ^{[2
]}

Plaza, Jose A. ^{[1
]}

机构：

[1] CSIC, IMB CNM, Inst Microelect Barcelona, Barcelona 08193, Spain

[2] CSIC, Ctr Invest Biol, Madrid 28040, Spain

[3] CSIC, IIQAB, ES-08034 Barcelona, Spain

来源：

SMALL | 2010年 / 6卷 / 04期

关键词：

biosensors; cells; microtechnology; nanoparticles; silicon chips; CHALLENGES; SYSTEM; NANOTECHNOLOGY; NANOPARTICLES; OPPORTUNITIES; SIZE;

D O I：

10.1002/smll.200901041

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Silicon-based chips offer high flexibility and versatility as they are based on semiconductor and MEMS technology. They can be top-down fabricated with well-controlled shape and size. Silicon microchips can be internalized into eukaryotic cells (see image) without interfering with cell viability. Engineered intracellular chips with different biomolecules attached to the surface can be used as intracellular sensors. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：499 / 502

页数：4

共 50 条

[1] Silicon chips detect intracellular pressure changes in living cells
Gomez-Martinez, Rodrigo
Hernandez-Pinto, Alberto M.
Duch, Marta
Vazquez, Patricia
Zinoviev, Kirill
de la Rosa, Enrique J.
Esteve, Jaume
Suarez, Teresa
Plaza, Jose A.
[J]. NATURE NANOTECHNOLOGY, 2013, 8 (07) : 517 - 521
[2] Silicon chips detect intracellular pressure changes in living cells
Gómez-Martínez R.
Hernández-Pinto A.M.
Duch M.
Vázquez P.
Zinoviev K.
De La Rosa E.J.
Esteve J.
Suárez T.
Plaza J.A.
[J]. Nature Nanotechnology, 2013, 8 (7) : 517 - 521
[3] Living Chips and Chips for the Living
Dekker, R.
Braam, S.
Henneken, V.
van der Horst, A.
Pakazad, S. Khoshfetrat
Louwerse, M.
van Meer, B.
Mimoun, B.
Savov, A.
van de Stolpe, A.
[J]. 2012 IEEE BIPOLAR/BICMOS CIRCUITS AND TECHNOLOGY MEETING (BCTM), 2012,
[4] Engineering living systems on chips: from cells to human on chips
Sei, Yoshitaka
Justus, Kyle
LeDuc, Philip
Kim, YongTae
[J]. MICROFLUIDICS AND NANOFLUIDICS, 2014, 16 (05) : 907 - 920
[5] Engineering living systems on chips: from cells to human on chips
Yoshitaka Sei
Kyle Justus
Philip LeDuc
YongTae Kim
[J]. Microfluidics and Nanofluidics, 2014, 16 : 907 - 920
[6] TRANSFER OF INTRACELLULAR IMMUNITY BY LIVING CELLS
FRENKEL, JK
[J]. FEDERATION PROCEEDINGS, 1966, 25 (2P1) : 596 - &
[7] FLUCTUATIONS IN LIVING CELLS AND INTRACELLULAR TRAFFIC
MIKHAILOV, A
HESS, B
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1995, 176 (01) : 185 - 192
[8] Detection of intracellular phosphatidylserine in living cells
Calderon, Frances
Kim, Hee-Yong
[J]. JOURNAL OF NEUROCHEMISTRY, 2008, 104 (05) : 1271 - 1279
[9] Living chips
Zubritksy, E
[J]. ANALYTICAL CHEMISTRY, 1999, 71 (17) : 591A - 592A
[10] CHANNELLESS CELLS OPTIMIZE SILICON USE IN SEMICUSTOM CHIPS
BURSKY, D
[J]. ELECTRONIC DESIGN, 1985, 33 (01) : 48 - +

← 1 2 3 4 5 →