Tacrolimus troughs in Caucasians with two CYP3A5 loss-of-function alleles: Evidence for additional genetic influences using a genome wide association study

被引：0
|
作者：
Oetting, W. S. [1 ]
Wu, B. [1 ]
Schladt, D. P. [2 ]
Guan, W. [1 ]
Remmel, R. P. [1 ]
Mannon, R. B. [3 ]
Matas, A. J. [1 ]
Israni, A. K. [4 ]
Jacobson, P. A. [1 ]
机构：
[1] Univ Minnesota, Minneapolis, MN USA
[2] Minneapolis Med Res Fdn Inc, Minneapolis, MN USA
[3] Univ Alabama, Birmingham, MN USA
[4] Hennepin Cty Med Ctr, Minneapolis, MN 55415 USA
来源：
EUROPEAN JOURNAL OF HUMAN GENETICS | 2018年 / 26卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P15.33A
引用
收藏
页码：695 / 696
页数：2
相关论文
共 6 条
  • [1] Differences in Tacrolimus Troughs and Doses Between Caucasians and African Americans with Two CYP3A5 Loss-of-Function Alleles: Looking Beyond CYP3A5 Expression.
    Oetting, W.
    Schladt, D.
    Guan, W.
    Remmel, R.
    Dorr, C.
    Sanghavi, K.
    Matas, A.
    Mannon, R.
    Israni, A.
    Jacobson, P.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 : 681 - 682
  • [2] Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles
    Oetting, W. S.
    Schladt, D. P.
    Guan, W.
    Miller, M. B.
    Remmel, R. P.
    Dorr, C.
    Sanghavi, K.
    Mannon, R. B.
    Herrera, B.
    Matas, A. J.
    Salomon, D. R.
    Kwok, P. Y.
    Keating, B. J.
    Israni, A. K.
    Jacobson, P. A.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 (02) : 574 - 582
  • [3] Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients
    W S Oetting
    B Wu
    D P Schladt
    W Guan
    R P Remmel
    R B Mannon
    A J Matas
    A K Israni
    P A Jacobson
    The Pharmacogenomics Journal, 2018, 18 : 501 - 505
  • [4] Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients
    Oetting, W. S.
    Wu, B.
    Schladt, D. P.
    Guan, W.
    Remmel, R. P.
    Mannon, R. B.
    Matas, A. J.
    Israni, A. K.
    Jacobson, P. A.
    PHARMACOGENOMICS JOURNAL, 2018, 18 (03): : 501 - 505
  • [5] A Prospective, Open-Label, Observational Clinical Cohort Study of the Association Between Delayed Renal Allograft Function, Tacrolimus Exposure, and CYP3A5 Genotype in Adult Recipients
    Kuypers, Dirk R. J.
    de Jonge, Hylke
    Naesens, Maarten
    Vanrenterghem, Yves
    CLINICAL THERAPEUTICS, 2010, 32 (12) : 2012 - 2023
  • [6] Influence of CYP3A5 Genetic Polymorphism on Long-Term Renal Function in Chinese Kidney Transplant Recipients Using Limited Sampling Strategy and Abbreviated Area Under the Curve for Tacrolimus Monitoring
    Cheung, Chi Yuen
    Chan, Koon Ming
    Wong, Yuen Ting
    Chak, Wai Leung
    Bekers, Otto
    van Hooff, Johannes P.
    PROGRESS IN TRANSPLANTATION, 2020, 30 (03) : 249 - 253
1