A highly efficient DBU-catalyzed green synthesis of spiro-oxindoles

被引：7
|
作者：
Wang, Liqun [1 ]
Zhang, Daming [1 ]
Li, Jian [1 ]
Xu, Guangyang [1 ]
Sun, Jiangtao [1 ]
机构：
[1] Changzhou Univ, Sch Pharmaceut Engn & Life Sci, Changzhou 213164, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 83期
基金：
中国国家自然科学基金;
关键词：
ENANTIOSELECTIVE SYNTHESIS; SPIROCYCLIC OXINDOLES; 3,3'-PYRROLIDONYL SPIROOXINDOLES; MICHAEL/CYCLIZATION REACTION; STEREOSELECTIVE-SYNTHESIS; ISOTHIOCYANATO OXINDOLES; BIOLOGICALLY IMPORTANT; ASYMMETRIC-SYNTHESIS; DOMINO REACTION; 3+2 ANNULATION;
D O I：
10.1039/c4ra08812c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A DBU-catalyzed green synthesis of spiro-oxindoles with 100% atom economy has been developed under environmentally benign conditions. This highly efficient transformation could be explained by its superior carbon basicity combined with nucleophilicity of DBU compared to other bases.
引用
收藏
页码：44193 / 44196
页数：4
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