Tubercular Uveitis: Nuggets from Collaborative Ocular Tuberculosis Study (COTS)-1

被引：23

作者：

Testi, Ilaria ^{[1
]}

Agrawal, Rupesh ^{[2
,3
,4
]}

Mahajan, Sarakshi ^{[5
]}

Agarwal, Aniruddha ^{[6
]}

Gunasekeran, Dinesh Visva ^{[2
,3
]}

Raje, Dhananjay ^{[7
]}

Aggarwal, Kanika ^{[6
]}

Murthy, Somasheila, I ^{[8
]}

Westcott, Mark ^{[1
]}

Chee, Soon Phaik ^{[4
,9
]}

McCluskey, Peter ^{[10
]}

Ho, Su Ling ^{[2
]}

Teoh, Stephen ^{[2
]}

Cimino, Luca ^{[11
]}

Biswas, Jyotirmay ^{[12
]}

Narain, Shishir ^{[13
]}

Agarwal, Manisha ^{[14
]}

Mahendradas, Padmamalini ^{[15
]}

Khairallah, Moncef ^{[16
]}

Jones, Nicholas ^{[17
]}

Tugal-Tutkun, Ilknur ^{[18
]}

Babu, Kalpana ^{[19
]}

Basu, Soumayava ^{[20
]}

Carreno, Ester ^{[21
]}

Lee, Richard ^{[22
]}

Al-Dhibi, Hassan ^{[23
]}

Bodaghi, Bahram ^{[24
]}

Invernizzi, Alessandro ^{[25
]}

Goldstein, Debra A. ^{[26
]}

Herbort, Carl P. ^{[27
]}

Barisani-Asenbauer, Talin ^{[28
]}

Gonzalez-Lopez, Julio J. ^{[29
]}

Androudi, Sofia ^{[30
]}

Bansal, Reema ^{[6
]}

Moharana, Bruttendu ^{[6
]}

Degli Esposti, Simona ^{[3
]}

Tasiopoulou, Anastasia ^{[1
]}

Nadarajah, Sengal ^{[1
]}

Agarwal, Mamta ^{[12
]}

Abraham, Sharanya ^{[12
]}

Vala, Ruchi ^{[15
]}

Singh, Ramandeep ^{[6
]}

Sharma, Aman ^{[31
]}

Sharma, Kusum ^{[32
]}

Zierhut, Manfred ^{[33
]}

Rousselot, Andres ^{[34
]}

Grant, Robert ^{[35
,36
]}

Kon, Onn Min ^{[37
]}

Cunningham, Emmett T. ^{[38
]}

Kempen, John ^{[39
,40
,41
]}

机构：

[1] NHS Fdn Trust, Moorfields Eye Hosp, London, England

[2] Tan Tock Seng Hosp, Natl Healthcare Grp, Eye Inst, Singapore, Singapore

[3] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore, Singapore

[4] Singapore Eye Res Inst, Singapore, Singapore

[5] Stanford Univ, Byers Eye Inst, Palo Alto, CA 94304 USA

[6] Postgrad Inst Med Educ & Res PGIMER, Adv Eye Ctr, Chandigarh, India

[7] MDS Bioanalyt, Nagpur, Maharashtra, India

[8] LV Prasad Eye Inst, Tej Kohli Cornea Inst, Hyderabad, India

[9] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore

[10] Univ Sydney, Cent Clin Sch, Save Sight Inst, Dept Clin Ophthalmol & Eye Hlth, Sydney, NSW, Australia

[11] Azienda USL IRCCS, Ocular Immunol Unit, Reggio Emilia, Italy

[12] Sankara Nethralaya, Dept Ophthalmol, Chennai, Tamil Nadu, India

[13] Shroff Eye Ctr, Dept Ophthalmol, New Delhi, India

[14] Dr Shroffs Char Eye Hosp Daryaganj, Dept Ophthalmol, New Delhi, India

[15] Narayana Nethralaya, Dept Uveitis & Ocular Immunol, Bangalore, Karnataka, India

[16] Univ Monastir, Fattouma Bourguiba Univ Hosp, Fac Med, Dept Ophthalmol, Monastir, Tunisia

[17] Univ Manchester, Dept Ophthalmol, Manchester, Lancs, England

[18] Istanbul Univ, Istanbul Fac Med, Dept Ophthalmol, Istanbul, Turkey

[19] Vittala Int Inst Ophthalmol, Prabha Eye Clin & Res Ctr, Bangalore, Karnataka, India

[20] LV Prasad Eye Inst, Dept Ophthalmol, Bhubaneswar, India

[21] Hosp Univ Fdn Jimenez Diaz, Dept Oftalmol, Madrid, Spain

[22] Bristol Eye Hosp, Dept Ophthalmol, Bristol, Avon, England

[23] King Khalid Eye Specialist Hosp, Dept Ophthalmol, Riyadh, Saudi Arabia

[24] Sorbonne Univ, Dept Ophthalmol, DHU SightRestore, Paris, France

[25] Univ Milan, Luigi Sacco Hosp, Dept Biomed & Clin Sci L Sacco, Eye Clin, Milan, Italy

[26] Northwestern Univ, Dept Ophthalmol, Feinberg Sch Med, Chicago, IL 60611 USA

[27] Univ Lausanne, Ctr Ophthalm Specialised Care, Lausanne, Switzerland

[28] Med Univ Vienna, Ctr Ocular Inflammat & Infect OCUVAC, Laura Bassi Ctr Expertise Ctr Pathophysiol Infect, Vienna, Austria

[29] Ramon & Cajal Univ Hosp, Dept Ophthalmol, Madrid, Spain

[30] Univ Thessaly, Dept Ophthalmol, Larisa, Greece

[31] PGIMER, Dept Rheumatol, Chandigarh, India

[32] PGIMER, Dept Microbiol, Chandigarh, India

[33] Univ Tubingen, Ctr Ophthalmol, Dept Ophthalmol, Tubingen, Germany

[34] Univ Salvador Buenos Aires, Dept Ophthalmol, Buenos Aires, DF, Argentina

[35] Kingston Univ, Fac Hlth Social Care & Educ, London, England

[36] St Georges Univ London, London, England

[37] Imperial Coll Healthcare NHS Trust, St Marys Hosp, Chest & Allergy Clin, London, England

[38] UCSF, Francis I Proctor Fdn, Sch Med, San Francisco, CA USA

[39] Harvard Med Sch, Dept Ophthalmol, Massachusetts Eye & Ear, Boston, MA 02115 USA

[40] MyungSung Christian Med Ctr, MCM Eye Unit, Addis Ababa, Ethiopia

[41] MyungSung Med Sch, Addis Ababa, Ethiopia

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2020年 / 28卷

关键词：

Anti-tubercular therapy; choroiditis; Collaborative Ocular Tuberculosis Study (COTS); global experts; tubercular uveitis; tuberculosis; INTRAOCULAR TUBERCULOSIS; DIAGNOSIS; THERAPY; COUNTRY;

D O I：

10.1080/09273948.2019.1646774

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Background: Tuberculosis (TB) is a major infection that can affect the eye as first and sole presentation without features of systemic disease. Controversy exists regarding diagnosis and management of tubercular uveitis (TBU), further compounded by regional variations in disease expression. Purpose: Collaborative Ocular Tuberculosis Study (COTS)-1 aims to address knowledge deficits through collaboration amongst uveitis specialists across the globe by sharing the data of patients with TBU presented at participating centers from January 2004 to December 2014. Methods: Data collection was facilitated by a novel method of real-time encrypted web-based data entry allowing regular updates as new data and recommendations become available. Results: Information on clinical features, investigation findings, management, and treatment outcomes were reviewed to get an idea about real world scenario. Conclusion: The current review aims to focus on methodology and briefing of published reports from COTS group in COTS-1 study to highlight key messages from this large data.

引用

页码：8 / 16

页数：9

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