Modulation of endometrial transforming growth factor β (TGFβ) by tamoxifen

被引：0
|
作者：
Carmichael, PL
Pole, JCM
Neven, P
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Sch Med, London SW7 2AZ, England
[2] Algemene Klin St Jan, Dienst Gynaecol & Verloskunde, B-1000 Brussels, Belgium
来源：
EUROPEAN JOURNAL OF CANCER | 2000年 / 36卷
关键词：
TGF beta; tamoxifen; breast; endometria;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Transforming growth factor beta (TGF beta) immunoreactivity was determined in endometria from non-drug-therapy and tamoxifen-treated patients. Sections were scored for pathology and quantity image analysis performed to determine levels of glandular- or fibrosis-associated TGF beta1. Tamoxifen-treated patients displayed greater levels of endometrial dysplasia and glandular hyperplasia, in addition to a statistically significant (P < 0.0001) elevation in gland-associated TGF<beta>1 protein. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：S42 / S43
页数：2
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