Pediatric craniopharyngioma

被引：61

作者：

Drapeau, Annie ^{[1
,2
]}

Walz, Patrick C. ^{[3
,4
]}

Eide, Jacob G. ^{[5
]}

Rugino, Alex J. ^{[6
]}

Shaikhouni, Ammar ^{[1
,2
]}

Mohyeldin, Ahmed ^{[2
]}

Carrau, Ricardo L. ^{[2
,3
]}

Prevedello, Daniel M. ^{[1
,2
,3
]}

机构：

[1] Nationwide Childrens Hosp, Dept Pediat Neurosurg, Columbus, OH USA

[2] Ohio State Univ, Dept Neurosurg, Wexner Med Ctr, Columbus, OH 43210 USA

[3] Ohio State Univ, Dept Otolaryngol, Wexner Med Ctr, Columbus, OH 43210 USA

[4] Nationwide Childrens Hosp, Dept Pediat Otolaryngol, 700 Childrens Dr, Columbus, OH 43205 USA

[5] Northwestern Univ, Feinberg Sch Med, Dept Otolaryngol, Chicago, IL USA

[6] OhioHlth Neurosurg, Columbus, OH USA

来源：

CHILDS NERVOUS SYSTEM | 2019年 / 35卷 / 11期

关键词：

Skull base; Pediatric; Endonasal; Craniopharyngioma; SKULL BASE SURGERY; QUALITY-OF-LIFE; SURGICAL-MANAGEMENT; ENDONASAL RESECTION; PITUITARY-GLAND; TOTAL REMOVAL; BETA-CATENIN; CHILDREN; OUTCOMES; EXPERIENCE;

D O I：

10.1007/s00381-019-04300-2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background Craniopharyngioma has historically been recognized to be a formidable pathology primarily due to its proximity to critical neurovascular structures and the challenging surgical corridors that surgeons have tried to reach this lesion. Focus of review In this work, we review the medical and surgical management of these tumors with a focus on clinical presentation, diagnostic identification, surgical approach, and associated adjuvant therapies. We will also discuss our current treatment paradigm using endoscopic, open, and combined approaches to craniopharyngiomas. The management of craniopharyngiomas requires a multidisciplinary team of surgeons, endocrinologists, and neuroanesthesiologists as well as neurocritical care specialists to deliver the most comprehensive and safest surgical resection with minimal postoperative morbidity.

引用

页码：2133 / 2145

页数：13

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