Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

被引：47

作者：

Foa, Robin ^{[1
]}

Chiaretti, Sabina ^{[1
]}

机构：

[1] Sapienza Univ, Dept Translat & Precis Med, Hematol, Rome, Italy

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2022年 / 386卷 / 25期

关键词：

MINIMAL RESIDUAL DISEASE; TERM-FOLLOW-UP; STEM-CELL TRANSPLANTATION; CHRONIC MYELOGENOUS LEUKEMIA; CHEMOTHERAPY PLUS DASATINIB; LOW-INTENSITY CHEMOTHERAPY; FRONT-LINE TREATMENT; HYPER-CVAD; TYROSINE KINASE; ADULT PATIENTS;

D O I：

10.1056/NEJMra2113347

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ph-Positive Acute Lymphoblastic Leukemia Until recently, Ph-positive ALL was very aggressive and difficult to treat. Current frontline therapy, based on tyrosine kinase inhibitors, glucocorticoids, and blinatumomab, has increased survival, with high-level clearance of measurable tumor cells.

引用

页码：2399 / 2411

页数：13

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