Spectrophotometric Method for Estimation of Leflunomide in Bulk and Tablets

被引：0
|
作者：
Pal, N. Rabindra [1 ]
Chakraborty, Manas [1 ]
Debnath, Rabindra [1 ]
Gupta, Bijan K. [1 ]
机构：
[1] Calcutta Inst Pharmaceut Technol & Allied Hlth Sc, Div Pharmaceut, Howrah 711316, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2010年 / 22卷 / 02期
关键词：
UV spectrophotometry; Leflunomide;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and sensitive UV spectrophotometric method for determination of leflunomide in bulk and tablets has been developed. Beer' law is obeyed in the concentration of 8-30 mcg/mL of leflunomide. The method was found to be simple, precise, accurate and cheap for routine analysis with recovery of 99.06 +/- 0.7593 %. The method does not require any separation of soluble excipient in the tablet as they do not interfere in the estimation. Results of analysis was verified statistically and by recovery studies thus the method can be used for routine, quality control of bulk and other formulations.
引用
收藏
页码：1649 / 1651
页数：3
相关论文
共 50 条
  • [1] Development and Validation of UV-Spectrophotometric Method for Estimation of Doxofylline in Bulk and Tablets
    Paul, Subrata
    Mia, Md Abdul Karim
    Sarker, Sabarni
    Biswas, Sheta
    Bal, Puja
    Dey, Trisha Rani
    Pal, Tarun Kumar
    [J]. ORIENTAL JOURNAL OF CHEMISTRY, 2020, 36 (05) : 908 - 914
  • [2] Spectrophotometric estimation of Bisoprolol Fumarate in bulk drug and tablets
    Sandip, Akmar
    Sonali, Paramane
    Lata, Kothapalli
    Asha, Thomas
    Sumitra, Jangam
    Mukesh, Mohite
    Avinash, Deshpande
    [J]. INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2007, 41 (04) : 353 - 357
  • [3] UV spectrophotometric method development and validation for estimation of furosemide in the bulk and tablets dosage form
    Chary, V. Padmabushana
    Sushmitha, G.
    Mani, B.
    Humera
    Chinnaeswaraiah, M.
    [J]. ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL, 2023, 12 (01): : 589 - 594
  • [4] Spectrophotometric method for determination of Bambuterol hydrochloride in bulk and tablets
    Pawar, Varun
    Lalitha, N.
    Puranik, S. B.
    Pai, P. N. Sanjay
    Rao, G. K.
    [J]. ORIENTAL JOURNAL OF CHEMISTRY, 2008, 24 (02) : 769 - 770
  • [5] SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF BISOPROLOL FUMARATE IN TABLETS
    Panainte, Alina Diana
    Bibire, Nela
    Tantaru, Gladiola
    Apostu, M.
    Vieriu, Madalina
    Dorneanu, V.
    [J]. MEDICAL-SURGICAL JOURNAL-REVISTA MEDICO-CHIRURGICALA, 2014, 118 (02): : 558 - 563
  • [6] Extractive spectrophotometric method for the estimation of telmisartan in tablets
    Vijayalakshmi, R.
    Applaraju, N.
    Dhanaraju, M. D.
    [J]. ORIENTAL JOURNAL OF CHEMISTRY, 2009, 25 (03) : 747 - 749
  • [7] Spectrophotometric determination of leflunomide in bulk and pharmaceutical formulations
    Babu, G. Srinu
    Babu, I. Sarat
    Kumar, N. Kiran
    Yugandhar, N. M.
    Paju, Ch. A. I.
    [J]. ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (02) : 1633 - 1635
  • [8] Spectrophotometric method for simultaneous estimation of paracetamol and piroxicam in tablets
    Shirkhedkar, A. A.
    Shaikh, Afsar
    Surana, S. J.
    [J]. ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (03) : 2470 - 2472
  • [9] DEVELOPMENT OF DIFFERENCE SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF LEFLUNOMIDE IN TABLET DOSAGE FORM
    Prabu, S. Lakshmana
    Prakash, T. N. K. Suriya
    Shanmugarathinam, A.
    [J]. CHEMICAL INDUSTRY & CHEMICAL ENGINEERING QUARTERLY, 2012, 18 (03) : 407 - 410
  • [10] Spectrophotometric Estimation of Bicalutamide in Tablets
    Sancheti, P. P.
    Vyas, V. M.
    Shah, Manali
    Karekar, Poonam
    Pore, Y. V.
    [J]. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2008, 70 (06) : 810 - 812
12345