Sickle cell disease (SCD) is a relatively common inherited disorder of haemoglobin with significant morbidity and mortality. This review describes the epidemiology and pathophysiology of the disease, and discusses the clinical manifestations found in children with SCD. A discussion of the evidence concerning the perioperative management of such children is presented.
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Heidelberg Univ, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care, D-68167 Mannheim, GermanyHeidelberg Univ, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care, D-68167 Mannheim, Germany
Frietsch, T
Ewen, I
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Heidelberg Univ, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care, D-68167 Mannheim, GermanyHeidelberg Univ, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care, D-68167 Mannheim, Germany
Ewen, I
Waschke, KF
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Heidelberg Univ, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care, D-68167 Mannheim, GermanyHeidelberg Univ, Fac Clin Med Mannheim, Dept Anesthesiol & Intens Care, D-68167 Mannheim, Germany
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AIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, IndiaAIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, India
Singh, Yudhyavir
Chabra, Alka
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Geetanjali Med Coll & Hosp, Dept Anesthesia & Crit Care, Udaipur, Rajasthan, IndiaAIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, India
Chabra, Alka
Venkateswaran, Vineeta
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AIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, IndiaAIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, India
Venkateswaran, Vineeta
Trikha, Anjan
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AIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, IndiaAIIMS, Anaesthesiol Crit Care & Pain Med, New Delhi 110029, India