Treatment of radiation-relapsing primary cutaneous B-cell lymphoma with an anti-CD20 monoclonal antibody

被引:17
|
作者
Lacouture, ME [1 ]
Baron, JM
Jani, AB
Laumann, AE
Soltani, K
机构
[1] Univ Chicago, Pritzker Sch Med, Dept Med, Dermatol Sect, Chicago, IL 60637 USA
[2] Univ Chicago, Pritzker Sch Med, Dept Med, Hematol Oncol Sect, Chicago, IL 60637 USA
[3] Univ Chicago, Pritzker Sch Med, Dept Radiat Oncol, Chicago, IL 60637 USA
关键词
D O I
10.1111/j.1365-2230.2004.01659.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Primary cutaneous B cell lymphomas have a high recurrence rate after treatment with surgery and/or local radiation therapy. Two men are described in whom radiotherapy-relapsing cutaneous B-cell lymphomas were successfully treated with the monoclonal anti-CD20 antibody rituximab. Both patients had a complete response with no recurrence at follow-up at 17 and 24 months for the large B-cell lymphoma of the leg and the follicle centre cell lymphoma, respectively. These are two of the few cases in the literature showing that rituximab is an effective and well-tolerated treatment for radiotherapy-relapsing primary cutaneous B cell lymphoma.
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页码:46 / 48
页数:3
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