Anti-Toxoplasma gondii antibodies in patients with schizophrenia-preliminary findings in a Turkish sample

被引:71
|
作者
Cetinkaya, Zafer
Yazar, Suleyman [1 ]
Gecici, Omer
Namli, Mustafa N.
机构
[1] Afyon Kocatepe Univ, Fac Med, Dept Microbiol, Afyon, Turkey
[2] Erciyes Univ, Dept Parasitol, Fac Med, TR-38039 Kayseri, Turkey
[3] Afyon Kocatepe Univ, Fac Med, Dept Psychiat, Afyon, Turkey
[4] Elazig Mental State Univ, Elazig, Turkey
关键词
schizophrenia; Toxoplasma gondii; ELISA;
D O I
10.1093/schbul/sbm021
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Schizophrenia is a serious neuropsychiatric disease of uncertain etiology. We investigated the seropositivity rate for anti-Toxoplasma IgG and IgNI antibodies by enzymelinked immunosorbent assay (ELISA) in patients with schizophrenia to ascertain a possible relationship between Toxoplasma gondii and schizophrenia. We selected 100 patients with schizophrenia, 50 with depressive disorder, and 50 healthy volunteers to investigate the seropositivity rate of anti-Toxoplasma antibodies by ELISA. The seropositivity rate for anti-Toxoplasma IgG antibodies among schizophrenia patients (66%) was significantly higher than among patients with depressive disorder or healthy volunteers (P <.01). Thus, there might be a causal relationship between toxoplasmosis and the etiology of schizophrenia.
引用
收藏
页码:789 / 791
页数:3
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