Laser-driven multi-degrees-of-freedom nanomanipulators produced by two-photon microstereolithography

Optically driven nanomanipulators with two degrees-of-freedom have been developed by using two-photon microstereolithography. The nanomanipulators are worked by maneuvering their movable component with a focused laser beam. To control the movement just by a single laser beam, the nanornanipulators is attached to a column-like structure named "Optical trapping point". Since the driving performance of the nanomanipulators depends on the shape and size of the optical trapping point, we have optimized the column-like optical trapping point. By the optimization of the optical trap point, the driving frequencies of translational motion and rotational motion were attained to 12 Hz and 120 rpm, respectively. The nanomanipulators also offers the torque on the order of fN to pN. Such optically driven nanomanipulation tools will be widely applied to micro/nano biotechnology and micro total analysis systems (mu-TAS).