Effects of microgravity and hypergravity on early developmental stages of Xenopus laevis

被引:0
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作者
Rizzo, AM [1 ]
Rossi, F [1 ]
Guerra, A [1 ]
Pippia, P [1 ]
Meloni, MA [1 ]
Berra, B [1 ]
机构
[1] Univ Milan, Inst Gen Physiol & Biochem, I-20134 Milan, Italy
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Q6 [生物物理学];
学科分类号
071011 ;
摘要
The aim of this work is to evaluate the development of X.l. in modified gravity conditions. The simulation of hyper and microgravity was performed utilizing: an hyperfuge, a Clinostat and later on a Random Positioning Machine (RPM, 3d Clinostat). The effect of hypergravity on embryos is significantly higher than that of microgravity; the exposure of embryos to 3xg for 3 days before and after hatch causes an activation of HSP-60 and HSP-70. Embryos exposed to 3xg during the first 3 days of development are very sensitive; and show a retard of development, with a lower content of DNA, neutral glycolipids and gangliosides compared to controls.
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页码:315 / 316
页数:2
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