A vestigial X open reading frame in duck hepatitis B virus

被引：8
|
作者：
Lin, B [1 ]
Anderson, DA [1 ]
机构：
[1] Maefarlane Burnet Ctr Med Res, Hepatitis Res Unit, Fairfield, Vic 3078, Australia
来源：
INTERVIROLOGY | 2000年 / 43卷 / 03期
关键词：
hepadnaviruses; duck hepatitis B virus; X gene;
D O I：
10.1159/000025037
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Duck hepatitis B virus (DHBV) appears to lack a homologue of the X protein found in mammalian hepadnaviruses. By replacing stop codons in the corresponding region of the DHBV genome, a hypothetical protein which closely matches the hydrophilicity profile of X proteins can be predicted, despite limited sequence homology. We conclude that a full-length X protein was once a common feature of the hepadnaviruses, conserved in structure bur not sequence. Copyright (C) 2000 S. Karger AG, Basel.
引用
收藏
页码：185 / 190
页数：6
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