Analysis of fractal-fractional model of tumor-immune interaction

被引:33
|
作者
Ahmad, Shabir [1 ]
Ullah, Aman [1 ]
Abdeljawad, Thabet [3 ,4 ,5 ]
Akgul, Ali [2 ]
Mlaiki, Nabil [3 ]
机构
[1] Univ Malakand, Dept Math, Dir L, Khyber Pakhtunk, Pakistan
[2] Siirt Univ, Art & Sci Fac, Dept Math, TR-56100 Siirt, Turkey
[3] Prince Sultan Univ, Dept Math & Gen Sci, POB 66833, Riyadh 11586, Saudi Arabia
[4] China Med Univ, Dept Med Res, Taichung 40402, Taiwan
[5] Asia Univ, Dept Comp Sci & Informat Engn, Taichung, Taiwan
关键词
Fractal-fractional operators; Fixed point theorems; Ulam-Hyres stability; CANCER-IMMUNOTHERAPY;
D O I
10.1016/j.rinp.2021.104178
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Recently, Atangana proposed new operators by combining the fractional and fractal calculus. These recently proposed operators, referred to as fractal-fractional operators, have been widely used to study the complex dynamics of a problem. Cancer is a prevalent disease today and is difficult to cure. The immune system tends to fight it as cancer sets up in the body. In this manuscript, the novel operators have been used to analyze the relationship between the immune system and cancer cells. The tumor-immune model has been studied qualitatively and quantitatively via Atangana-Baleanu fractal-fractional operator. The existence and uniqueness results of the model under Atangana-Baleanu fractal-fractional operator have proved through fixed point theorems. The Ulam-Hyres stability for the model has derived through non-linear analysis. Numerical results have developed through Lagrangian-piece wise interpolation for the different fractal-fractional operators. To visualize the relationship between immune cells and cancers cells under novel operators in a various sense, we simulate the numerical results for the different sets of fractional and fractal orders.
引用
收藏
页数:11
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