A Piece in the Puzzle of Personalized Medicine

被引：12
|
作者：
Kroemer, H. K. [1 ]
Schwabedissen, H. E. Meyer Zu [1 ]
机构：
[1] Ernst Moritz Arndt Univ Greifswald, Ctr Pharmacol & Expt Therapy, Dept Pharmacol, Greifswald, Germany
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2010年 / 87卷 / 01期
关键词：
PHARMACOKINETICS; VARIANTS;
D O I：
10.1038/clpt.2009.219
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Predicting individual drug response based on inherited factors remains a major challenge. Some examples of significant contributions of single genetic variants to overall therapeutic success of drugs in complex diseases are currently emerging. For most compounds, however, multiple genetic and nongenetic factors will modify drug action. Comprehensive integration of these factors will determine the role of pharmacogenomics for personalized medicine.
引用
收藏
页码：19 / 20
页数：2
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