Abusive head injury in the very young: outcomes from a Singapore children's hospital

被引:1
|
作者
Primalani, Nishal Kishinchand [1 ]
Chan, Yiong Huak [2 ]
Ng, Zhi Min [3 ]
Chong, Shu-Ling [4 ]
Seow, Wan Tew [1 ,5 ,6 ]
Loh, Lik Eng [7 ]
Mok, Yee Hui [7 ]
Low, Sharon Y. Y. [1 ,5 ,6 ]
机构
[1] KK Womens & Childrens Hosp, Neurosurg Serv, 100 Bukit Timah Rd, Singapore 229899, Singapore
[2] Natl Univ Singapore, Clin Res Ctr, Yong Loo Lin Sch Med, CBmE Off,Biostat Unit, Block MD11,02-03,10 Med Dr, Singapore 117597, Singapore
[3] KK Womens & Childrens Hosp, Dept Paediat, Neurol Serv, Singapore, Singapore
[4] KK Womens & Childrens Hosp, Childrens Emergency, Singapore, Singapore
[5] Natl Neurosci Inst, Dept Neurosurg, Singapore, Singapore
[6] SingHlth Duke NUS Neurosci Acad Clin Program, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
[7] KK Womens & Childrens Hosp, Childrens Intens Care Unit, 100 Bukit Timah Rd, Singapore 229899, Singapore
关键词
Abusive head injury; Non-accidental head injury; Paediatric head injury; TRAUMATIC BRAIN-INJURY; SUBDURAL HEMORRHAGES; BENIGN ENLARGEMENT; EXTERNAL HYDROCEPHALUS; NONACCIDENTAL TRAUMA; INFANTS; DEMOGRAPHICS; PLASTICITY; MECHANISMS; IMPACT;
D O I
10.1007/s00381-022-05572-x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose Abusive head trauma (AHT) is a serious problem in children. The aims of this study are to identify risk factors that correlate with outcomes for those requiring neurosurgical intervention for very young children with AHT, assessment of variables associated with outcomes, and corroboration of our results with literature. Methods This is an ethics-approved, retrospective study. Inclusion criteria consisted of patients aged 2 years old or less with a diagnosis of AHT managed by the Neurosurgical Service, KK Women's and Children's Hospital. Demographical and clinical variables are incorporated in the statistical analyses. Logistic regression was applied to statistically significant variables for the risk prediction model. Results From 2000 to 2020, 24 patients required surgery for AHT. Timepoint was set at 12 months post-diagnosis. Univariate analyses demonstrated that patients with mild TBI were likely to have a favourable GOS-E Peds (p = 0.01), whereas radiological presence of cerebral oedema (p < .001), development of scar epilepsy (p = 0.021), and progression to cerebral palsy (p = 0.001) were associated with unfavourable GOS-E Peds. Conclusion This is the first study focused on neurosurgical outcomes for very young children with AHT in Singapore. We advocate multidisciplinary efforts to improve outcomes for this devastating condition.
引用
收藏
页码:2397 / 2407
页数:11
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