Self-assembled Cyclodextrin Metal-Organic Frameworks on Graphene Oxide as Filter Membrane for Trace-level Naringin Pre-enrichment before Analysis

A green, renewable composite was designed and fabricated based on self-assembly of cyclodextrin metal-organic framework (CD-MOF) on graphene oxide(GO). Then, the GO@CD-MOF was embedded in 0.45 mu m PTFE membrane to produce a dual-functional membrane which could carry out sample enrichment by capturing naringin molecules. The membrane filter was further improved by investigating the effects of the experimental parameters including amount of GO@CD-MOF, enrichment time and elution solvent on enrichment efficiency of naringin. Further, the present method had been successfully applied to citrus sample and obtained satisfied recovery value (79.7%-100.3%). Moreover, the extraction of naringin can be achieved for 2 min, and GO@CD-MOF loaded membrane can be reused at least for 5 times. The results demonstrate that the fabrication of the novel filter membrane based on GO@CD-MOF is a fast, simple and reliable, and possesses great potential in the determination of naringin from real samples by dual-function of separation and enrichment.