Oral Malignant Melanoma in a Patient With Neurofibromatosis Type 1: An Extremely Rare Association

被引:0
|
作者
Berhili, Soufiane [1 ,2 ]
Rezzoug, Mohammed [2 ,3 ]
Ben Sghier, Ahmed [2 ]
Moukhlissi, Mohammed [2 ,4 ]
Mezour, Loubna [2 ,4 ]
机构
[1] Mohammed First Univ, Fac Med & Pharm, Oujda, Morocco
[2] Mohammed VI Univ Hosp, Dept Radiat Oncol, Hassan II Oncol Ctr, Oujda, Morocco
[3] Mohammed Premier Univ, Fac Sci, LPMR, Oujda, Morocco
[4] Mohammed Premier Univ, Fac Med & Pharm, Oujda, Morocco
关键词
rare association; von recklinghausen disease; radiotherapy; neurofibromatosis type 1; oral melanoma; MUCOSAL MELANOMA; ANORECTAL MELANOMA; RADIATION-THERAPY; LOCAL EXCISION; BENIGN-TUMORS; RADIOTHERAPY; HEAD; NECK; MANAGEMENT; PROGNOSIS;
D O I
10.7759/cureus.25331
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Neurofibromatosis type 1 (NF1) is a genetic disorder associated with high rates of neural crest-derived tumors, both benign and malignant. Many series have identified cutaneous melanoma as a rare tumor among cancers occurring in individuals with NF1 disease, but the mucosal location has to date never been reported. In this paper, we report an oral melanoma occurring in a patient with NF1 disorder, diagnosed at a locally advanced stage, successfully managed by definitive external beam radiotherapy, along with a comprehensive literature review on the melanoma-NF1 association.
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页数:9
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