PROSTATE CANCER Androgen deprivation therapy and bone loss

被引：2
|
作者：
Amir, Eitan
Tannock, Ian F. [1 ]
机构：
[1] Princess Margaret Hosp, Div Med Oncol & Hematol, Toronto, ON M5G 2M9, Canada
来源：
NATURE REVIEWS UROLOGY | 2009年 / 6卷 / 12期
关键词：
MULTIPLE-MYELOMA; ZOLEDRONIC ACID; MEN; DENOSUMAB; PREVENT; METASTASES; FRACTURE; BREAST; TRIAL;
D O I：
10.1038/nrurol.2009.218
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Denosumab, an inhibitor of RANKL, improves bone mineral density and reduces the incidence of fractures in men who receive androgen deprivation therapy (ADT) for prostate cancer. At present, however, a lack of comparison with potent bisphosphonates limits the assessment of its utility in the prevention of ADT-induced bone loss.
引用
收藏
页码：642 / 644
页数：4
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