Potent Phytomolecules Against the RNA Dependent RNA Polymerase of the SARS-COV-2

The 2019 Novel coronavirus (2019-nCoV) threatens public health. The 2019-nCoV is also referred to as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Specific drug against the virus is yet to be discovered. Development of pharmacophores for proficient treatment against severe acute SARS-CoV-2 is challenging. The solved cryo-EM structure of SARS-CoV-2 RNA dependent RNA polymerase (RdRp) can be used as one of the primary target molecule and possible inhibitory ligands may be screened using in silico molecular docking. Primarily phytochemicals can be screened to detect any potential bio active molecules. In silico molecular docking revealed that the phytochemical, Quercitin may effectively bind to the active site of the SARS-CoV-2 main protease.