Microsecond-long MD simulations of substrate occlusion by the human dopamine transporter

被引：0
|
作者：
Silva, Leticia A. [1 ]
Stockner, Thomas [1 ]
机构：
[1] Med Univ Vienna, Inst Pharmacol, Ctr Physiol & Pharmacol, Vienna, Austria
来源：
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS | 2021年 / 50卷 / SUPPL 1期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
P-60
引用
收藏
页码：110 / 110
页数：1
相关论文
共 21 条
  • [1] Lipid uptake/release by start domains from microsecond-long molecular dynamics simulations
    Moqadam, Mahmoud
    Talandashti, Reza
    Gartan, Parveen
    Gavin, Anne-Claude
    Reuter, Nathalie
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 452A - 452A
  • [2] Structural dataset from microsecond-long simulations of yeast mitofusin Fzo1 in the context of membrane docking
    Brandner, Astrid
    De Vecchis, Dario
    Baaden, Marc
    Cohen, Mickael M.
    Taly, Antoine
    DATA IN BRIEF, 2019, 26
  • [3] Which form of dopamine is the substrate for the human dopamine transporter: The cationic or the uncharged species?
    Berfield, JL
    Wang, LJC
    Reith, MEA
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (08) : 4876 - 4882
  • [4] Substrate transport and cocaine binding of human dopamine transporter is reduced by substitution of carboxyl tail with that of bovine dopamine transporter
    Lee, SH
    Cho, HK
    Son, H
    Lee, YS
    NEUROREPORT, 1997, 8 (11) : 2591 - 2594
  • [5] ATP-dependent substrate occlusion by the human erythrocyte sugar transporter
    Heard, KS
    Fidyk, N
    Carruthers, A
    BIOCHEMISTRY, 2000, 39 (11) : 3005 - 3014
  • [6] The molecular mechanism of substrate-triggered occlusion in the human serotonin transporter
    Gradisch, Ralph
    Szoellosi, Daniel
    Sitte, Harald H.
    Stockner, Thomas
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2021, 50 (SUPPL 1): : 106 - 106
  • [7] Structure-activity relationships for substrate recognition by the human dopamine transporter
    Appell, M
    Berfield, JL
    Wang, LJC
    Dunn, WJ
    Chen, NH
    Reith, MEA
    BIOCHEMICAL PHARMACOLOGY, 2004, 67 (02) : 293 - 302
  • [8] Insights into the Dynamics of the Human Zinc Transporter ZnT8 by MD Simulations
    Sala, Davide
    Giachetti, Andrea
    Rosato, Antonio
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2021, 61 (02) : 901 - 912
  • [9] Free energy profile of the substrate-induced occlusion of the human serotonin transporter
    da Silva, Leticia Alves
    Lazzarin, Erika
    Gradisch, Ralph
    Clarke, Amy
    Stockner, Thomas
    JOURNAL OF NEUROCHEMISTRY, 2024, 168 (09) : 1993 - 2006
  • [10] Probing binding and occlusion of substrate in the human creatine transporter-1 by computation and mutagenesis
    Clarke, Amy
    Farr, Clemens V.
    El-Kasaby, Ali
    Szoellosi, Daniel
    Freissmuth, Michael
    Sucic, Sonja
    Stockner, Thomas
    PROTEIN SCIENCE, 2024, 33 (01)
123