Molecular mechanisms of muscle atrophy

被引：129

作者：

McKinnell, LW ^{[1
]}

Rudnicki, MA ^{[1
]}

机构：

[1] Ottawa Hlth Res Inst, Ottawa, ON K1H 8L6, Canada

来源：

CELL | 2004年 / 119卷 / 07期

关键词：

D O I：

10.1016/j.cell.2004.12.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Skeletal muscle atrophy has extreme adverse consequences. Molecular mechanisms that mediate the process of atrophy are not well defined. Recent studies have focused on diverse molecular cascades that control the activation of ubiquitin ligases, indicating that the involvement of the ubiquitin proteasome may be common to a range of atrophic stimuli.

引用

页码：907 / 910

页数：4

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